Monolina Shil on Muck Rack

Monolina Shil

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Articles

Diverse priming outcomes under conditions of very rare precursor B cells

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By Patrick Madden, Ester Marina-Zárate, Kristen A. Rodrigues, Jon M. Steichen, Monolina Shil, Kaiyuan Ni, Katarzyna Kaczmarek Michaels, Laura Maiorino, Swati Saha, Arpan Pradhan, Oleksandr Kalyuzhiny, Alessia Liguori, Paul Lopez, Ivy Phung, Claudia Flynn, Mariane B. Melo, Nicole Phelps Verified, Erik Georgeson, Michael Kubitz, Danny Lu, Amanda R. Metz, Oscar Rodriguez, Oscar Rodríguez, Óscar Rodríguez, Kaitlyn T Shields, Steven R. Schultze, Melissa Smith, Vanessa R. Lewis, Elana Ben-Akiva, William P. Pinney, Justin Gregory, Shuhao Xiao, Diane G. Carnathan, Sudhir Pai Kasturi, Corey T. Watson, Steven E. Bosinger, Guido Silvestri, William R. Schief, Darrell J. Irvine, Shane Crotty, Ashley Lemnios, Nushin Alavi, Saman Eskandarzadeh, Brandon S. Healy, Deuk Lim
| Cell Press Verified
Keywords naive B cells bnAb precursors germline-targeting adjuvants escalating dose HIV vaccines HIV bnAbs BG18 Introduction The aim of many vaccines against viruses is to induce neutralizing antibodies that protect against infection.1,2,3 B cell precursors that give rise to these types of neutralizing responses can be extremely rare in the naive B cell repertoire and infrequently participate in immune responses.4,5,6,7,8,9,10,11,12 Germline-targeting vaccine design is one approach to prime...
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