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Melissa Smith on Muck Rack

Melissa Smith

  • Media Relations Specialist, The Humane Society of the United States
Traverse City
As seen in: Wiley Online Library, Memory Studies, Applied Animal Behaviour Science, MDPI, SAGE Publishing, ACS Publications, Science Magazine, Cell Press, The Four, WWTV-TV (Cadillac, MI) and
Cat mom🤍 Former TV news journalist / Forever animal@welfare advocate / michiganstateu alum #AcousticNeuromaWarrior 🧠
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Articles

B cells gone broad: A deep dive into SARS-CoV-2 antibody breadth

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By Wenhui Li, Yuxi Wei, Mieke Metzemaekers, Easton E. Ford, Melissa Smith
| Science Magazine Verified
Abstract Antigen-specific B cell profiling uncovers key determinants of SARS-CoV-2 antibody breadth after infection and vaccination.
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Population-level genomic analysis of immunoglobulin loci variation in rhesus macaques reveals extensive germline diversity

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By Ayelet Peres, Amit Upadhyay, Vered Klein, Swati Saha, Oscar Rodriguez, Oscar Rodríguez Verified, Óscar Rodríguez Verified, Zachary M. Vanwinkle, Kirti A. Karunakaran, Amanda R. Metz, William A. Lauer, Mark Lin, Timothy L. Melton, Lukas Granholm, Pazit Polak, Samuel M. Peterson, Eric Peterson, Nagarajan Raju, Kaitlyn T Shields, Steven R. Schultze, Adam J. Ericsen, Stacey A. Lapp, Francois Villinger, Mats Ohlin, Christopher A. Cottrell, Rama R. Amara, Cynthia A. Derdeyn, Shane Crotty, William R. Schief, Melissa Smith, William Lees, Corey T. Watson, Gur Yaari, Steven E. Bosinger, Thang Ton
| Cell Press Verified
Keywords immunoglobulins rhesus macaque broadly neutralizing antibodies repertoire database genomics germline inference antibodies HIV B cell receptor Introduction The extraordinary diversity of B cell receptors (BCRs) underpins the adaptive immune system’s ability to recognize a vast range of foreign antigens and produce high-affinity, neutralizing antibodies.1 In mammals, BCRs are encoded by an extensive gene family that resides within three immunoglobulin (IG) loci: the heavy-chain locus...
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Diverse priming outcomes under conditions of very rare precursor B cells

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By Patrick Madden, Ester Marina-Zárate, Kristen A. Rodrigues, Jon M. Steichen, Monolina Shil, Kaiyuan Ni, Katarzyna Kaczmarek Michaels, Laura Maiorino, Swati Saha, Arpan Pradhan, Oleksandr Kalyuzhiny, Alessia Liguori, Paul Lopez, Ivy Phung, Claudia Flynn, Mariane B. Melo, Nicole Phelps Verified, Erik Georgeson, Michael Kubitz, Danny Lu, Amanda R. Metz, Oscar Rodriguez, Oscar Rodríguez, Óscar Rodríguez, Kaitlyn T Shields, Steven R. Schultze, Melissa Smith, Vanessa R. Lewis, Elana Ben-Akiva, William P. Pinney, Justin Gregory, Shuhao Xiao, Diane G. Carnathan, Sudhir Pai Kasturi, Corey T. Watson, Steven E. Bosinger, Guido Silvestri, William R. Schief, Darrell J. Irvine, Shane Crotty, Ashley Lemnios, Nushin Alavi, Saman Eskandarzadeh, Brandon S. Healy, Deuk Lim
| Cell Press Verified
Keywords naive B cells bnAb precursors germline-targeting adjuvants escalating dose HIV vaccines HIV bnAbs BG18 Introduction The aim of many vaccines against viruses is to induce neutralizing antibodies that protect against infection.1,2,3 B cell precursors that give rise to these types of neutralizing responses can be extremely rare in the naive B cell repertoire and infrequently participate in immune responses.4,5,6,7,8,9,10,11,12 Germline-targeting vaccine design is one approach to prime...
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