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Morten L. Kringelbach

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Articles

How to Build Better Digital Twins of the Human Brain

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By Andrea Luppi, Gustavo Deco, Morten L. Kringelbach
| Singularity Hub Verified
The potential to create personalized digital twins of your brain and body is a hot topic in neuroscience and medicine today. These computer models are designed to simulate how parts of your brain interact and how the brain may respond to stimulation, disease, or medication. The extraordinary complexity of the brain's billions of neurons makes this a very difficult task, of course, even in the era of AI and big data.
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How to build a digital ‘twin’ of the human brain – what existing models overlook Original

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By Andrea Luppi, Gustavo Deco, Morten L. Kringelbach
| The Conversation Verified
The potential to create personalised digital “twins” of your brain and body is a hot topic in neuroscience and medicine today. These computer models are designed to simulate how parts of your brain interact, and how the brain may respond to stimulation, disease or medication. The extraordinary complexity of the brain’s billions of neurons makes this a very difficult task, of course, even in the era of AI and big data.
Open in Who Shared View Duplicates (6) Issue with article?

Competitive interactions shape mammalian brain network dynamics and computation

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By Andrea Luppi, Yonatan Sanz Perl, Jakub Vohryzek, Hana Ali, Pedro Mediano, Fernando Rosas, Filip Milisav, Laura E Suarez, Silvia Gini, Daniel Gutierrez-Barragan, Yohan Yee, Sean Froudist-Walsh, Alessandro Gozzi, Bratislav Misic, Gustavo Deco, Morten L. Kringelbach
| Nature Verified
Abstract How does brain network architecture balance cooperation and competition between distributed circuits? Here we use computational whole-brain modeling to examine the dynamical and computational relevance of cooperative and competitive interactions in the mammalian connectome. Across human, macaque and mouse, we show that to faithfully reproduce brain activity, model architecture consistently combines modular cooperative interactions with diffuse, long-range competitive interactions.
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