Muktar Ibrahim on Muck Rack

Muktar Ibrahim

Africa
As seen in: Nature, The Journal of Clinical Investigation

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Articles

BPZE1 vaccination induces IL-17 + and IL-22 + CD4 + T cells associated with nasal mucosal secretory IgA responses in humans: effects on virulent Bordetella pertussis colonisation

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By Diane Gbesemete, Tyween Jia Coutinho, Muktar Ibrahim, Jay R. Laver, Peter Goldstein, Stephanie Noviello, Keith Rubin, Saul N Faust, Camille Locht, Robert C Read, Adam P. Dale
| Nature
Abstract Pertussis remains a major public health challenge due to the inability of current acellular vaccines to prevent Bordetella pertussis colonisation and transmission. The live-attenuated intranasal vaccine, BPZE1, has shown efficacy in protecting against infection following challenge with virulent B. pertussis, but the immune mechanisms underpinning this protective effect are poorly defined.
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