Skip To Main Content
Naama Barkai on Muck Rack

Naama Barkai

As seen in: Nature, Science Magazine, BioRxiv, Cell Press, Cell Reports, Genome Research, eLife
Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work. Claim your profile

Get in touch with Naama

Contact Naama, search articles and posts on X, monitor coverage, and track replies from one place.

Learn more about Muck Rack

Actions

Share this page

Is this you?

As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile

Articles

Engineering intrinsically disordered regions for guiding genome navigation

|
By Jing Liu, Divya Kumar Verified, Bohdana Hurieva, Felix Jonas, Naama Barkai
| Cell Press Verified
Keywords intrinsically disordered regions transcription factors synthetic biology gene regulation ChEC-seq Introduction Proteins are conventionally described as “molecular machines” that perform defined cellular functions by folding into specific structures.
Open in Who Shared Issue with article?

Design principles of transcription factors with intrinsically disordered regions

|
By Wencheng Ji, Ori Hachmo, Naama Barkai, Ariel Amir
| eLife
eLife Assessment This paper presents an important theoretical exploration of how a flexible protein domain with multiple DNA binding sites may simultaneously provide stability to the DNA-bound state and enables exploration of the DNA strand. The authors propose a mechanism ("octopusing") for protein doing a random walk while bound to DNA which simultaneously enables exploration of the DNA strand and enhances the stability of the bound state.
Open in Who Shared Issue with article?

Intrinsically disordered regions as facilitators of the transcription factor target search - Nature Reviews Genetics

|
By Felix Jonas, Naama Barkai
| Nature Verified
Abstract Transcription factors (TFs) contribute to organismal development and function by regulating gene expression. Despite decades of research, the factors determining the specificity and speed at which eukaryotic TFs detect their target binding sites remain poorly understood. Recent studies have pointed to intrinsically disordered regions (IDRs) within TFs as key regulators of the process by which TFs find their target sites on DNA (the TF target search).
Open in Who Shared Issue with article?
See all 12 articles