Naomi Thomas on Muck Rack

Naomi Thomas

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Articles

Mavodelpar in patients with primary mitochondrial myopathy: a phase 1 trial

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By Renae Stefanetti, Chiara Pizzamiglio, Alasdair Blain, Lisa Alcock, Gavin Hudson, Jane Newman, Naomi Thomas, Charlotte Warren, Philip Brown, David Houghton, Heather Hunter, Albert Lim, Yi Shiau Ng, Catherine L. Feeney, Louise Germain, Enrico Bugiardini, Michael Hanna, Robert E. McFarland, Grainne Gorman, Gráinne S. Gorman, Huizhong Su, Helen A. L. Tuppen, Iwona Skorupinska, Robert D. S. Pitceathly
| Nature Verified
Abstract Primary mitochondrial myopathies (PMM) are rare, genetically-defined disorders characterised by defects of oxidative phosphorylation, predominantly affecting skeletal muscle. This Phase 1b open-label trial evaluated mavodelpar, a selective peroxisome proliferator-activated receptor delta (PPARδ) agonist, over 12 weeks (Part A), with an optional 36 week extension (Part B) in adults with PMM.
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New study links COVID-19 vaccination to a small, temporary change in menstrual cycles

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By Naomi Thomas
| Denison Bulletin & Review Verified
People who got the COVID-19 vaccine reported slightly longer menstrual cycles, but the change was temporary, according to a new study published Tuesday in the journal BMJ Medicine. "Compared with the unvaccinated group, vaccinated individuals had an adjusted increase in menstrual cycle length of less than one day with both first and second vaccine doses," wrote the study authors, from universities in Oregon, Massachusetts, London and Edinburgh.
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