Robert E. McFarland on Muck Rack

Robert E. McFarland

As seen in: Color Research & Application, Nature, Wiley Online Library, Podbean, The New England Journal of Medicine, Cell Metabolism, The American Journal of Human Genetics, The Lancet, Belfast News Letter, OnTableTop and
Husband. Father. Best Selling Author. Executive Coach. Business Growth Expert. Leadership Consultant. Conference Speaker. Making ideals actionable.
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Articles

Mavodelpar in patients with primary mitochondrial myopathy: a phase 1 trial

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By Renae Stefanetti, Chiara Pizzamiglio, Alasdair Blain, Lisa Alcock, Gavin Hudson, Jane Newman, Naomi Thomas, Charlotte Warren, Philip Brown, David Houghton, Heather Hunter, Albert Lim, Yi Shiau Ng, Catherine L. Feeney, Louise Germain, Enrico Bugiardini, Michael Hanna, Robert E. McFarland, Grainne Gorman, Gráinne S. Gorman, Huizhong Su, Helen A. L. Tuppen, Iwona Skorupinska, Robert D. S. Pitceathly
| Nature
Abstract Primary mitochondrial myopathies (PMM) are rare, genetically-defined disorders characterised by defects of oxidative phosphorylation, predominantly affecting skeletal muscle. This Phase 1b open-label trial evaluated mavodelpar, a selective peroxisome proliferator-activated receptor delta (PPARδ) agonist, over 12 weeks (Part A), with an optional 36 week extension (Part B) in adults with PMM.
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Bi-allelic ATG12 variants impair autophagy and cause a neurodevelopmental disorder

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By Shotaro Asano, Yuxiang Huang, Fumi Suomi, Tomoya Eguchi, Cassidy Petree, Kevin Huang, Magali Prigent, Thomas J. McCorvie, Daniel Warren, Emma Hobson, Helen McCullagh, Doriana Misceo, Anna Bjerre, Claus Klingenberg, Eirik Frengen, Swati Naik, Gavin Ryan, Katherine Foster, Pradeep Vasudevan, Rajib Samanta, Fatima Rahman, Shazia Maqbool, Vrajesh Udani, Stephanie Efthymiou, Henry Houlden, Robert E. McFarland, Jack Collier, Reza Maroofian, Wyatt W. Yue, Gaurav K. Varshney, Daniel J. Klionsky, Renaud Legouis, Thomas G. McWilliams, Noboru Mizushima, Monika Oláhová, Charlotte L. Alston, Robert Taylor, James Lambton, Aliza Imam, Marie F. Smeland, Annapurna Sudarsanam
| The American Journal of Human Genetics
Keywords ataxia ATG12 autophagy cerebellar hypoplasia global developmental delay Introduction Autophagy is a cellular degradation and recycling process that sustains eukaryotic homeostasis.
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2026 Robert McFarland

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By Robert E. McFarland
| hudl.com
Oops! It looks like AdBlock or a similar tool has prevented this page from loading. Please disable the plugin for all Hudl.com pages and refresh your browser. 206 views | 7:32 | Nov 17, 2025
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