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Narumi Ogonuki on Muck Rack

Narumi Ogonuki

As seen in: Nature, PNAS, Science Magazine, BioRxiv, Stem Cell Reports, eLife, The Journal of Clinical Investigation
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Articles

Messenger RNA delivery into Sertoli cells restores fertility to congenitally infertile male mice

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By Mito Kanatsu-Shinohara, Narumi Ogonuki, Shogo Matoba, Takehiro Miyazaki, Hiroko Morimoto, Tianjiao Liu, Naoto Yoshinaga, Atsuo Ogura, Satoshi uchida, Takashi Shinohara
| Stem Cell Reports Verified
ResourceOnline now102829Open access Affiliations & Notes 1Department of Molecular Genetics, Graduate School of Medicine, Kyoto University, Kyoto 606-8501, Japan 2RIKEN, BioResource Research Center, Tsukuba 305-0074, Japan 3Biomacromolecule Research Team, RIKEN Center for Sustainable Resource Science, Wako-shi, Saitama 351-0198, Japan 4Department of Advanced Nanomedical Engineering, Medical Research Institute, Tokyo Medical and Dental University, Tokyo, Japan 5Innovation Center of NanoMedicine...
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Generation of functionally competent testicular somatic cells from pluripotent stem cells

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By Takuya Sato, J. Raouf Belkhir, Johannes Spaethe, Takashi Yoshino, Takahiro Suzuki, Takafumi Matsumura, Yu Ishikawa-Yamauchi, Haruka Yabukami, Yoshiakira Kanai, Yuichi Shima, Makoto Tachibana, Shogo Matoba, Kimiko Inoue, Narumi Ogonuki, Mai Ohtsuka, Yuki Matsudaira, Shiori Maeda, Miki Inoue
| Science Magazine Verified
Abstract Cellular interactions between germ cells and gonadal somatic cells are essential for the progression of gametogenesis. Here, we report a culture method for generating fetal testicular somatic cell–like cells (fTeSLCs) from embryonic stem cells. These fTeSLCs exhibit a transcriptomic profile closely resembling that of their in vivo counterparts, including distinct cell populations corresponding to Sertoli cells and interstitial cells.
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Reverse transcriptase inhibitors enable the generation of fertile spermatids from fetal mouse testes in vitro

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By Yu Ishikawa-Yamauchi, Takafumi Matsumura, Mitsuru Komeya, Shogo Matoba, Kimiko Inoue, Narumi Ogonuki, Atsuo Ogura, Takehiko Ogawa, Takuya Sato, Mayuka Nishida, Yukina Ono-Sunagare, Sayuri Kato
| Nature Verified
Abstract Organ culture systems enabling in vitro spermatogenesis from neonatal mouse testes exist, but differentiation from fetal testes shortly after sex determination remains unsuccessful. Here, we report the in vitro generation of fertile haploid cells from E12.5 fetal testes.
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