Natalie Lo

Abstract Few studies have characterized immune correlates of SARS-CoV-2 infection risk in children, particularly those with hybrid immunity from vaccination and prior infection. We conduct a prospective community-based cohort study of 1509 U.S. children (2022–2024), performing weekly SARS-CoV-2 PCR testing and measuring baseline binding and neutralizing antibody titers against multiple variants.

Abstract Genotoxic anticancer therapies exploit the heightened DNA replication stress of cancer cells. Members of the phosphoinositide-3-kinase-related kinase (PIKK) family, including ATR, ATM and DNA-PKcs, orchestrate the DNA damage response at stalled and broken replication forks, triggering complex signaling cascades that dictate cell fate.

For the majority of my life, gymnastics has been central and significant. I started competitive gymnastics in elementary school and competed through my senior year of high school. Practices were up to four hours, and gymnastics season was all year long. During high school, I started coaching gymnastics, so I was at the gym five days a week, either coaching, practicing or both. When I moved across the country, I stopped gymnastics entirely.