After the acceptance by the US Food and Drug Administration (FDA) of a Biologics License Application (BLA) for imsidolimab in generalized pustular psoriasis (GPP) was announced, the HCPLive editorial team spoke in an interview with a dermatology leader regarding this move’s significance for patients with GPP.1,2 Vanda Pharmaceuticals' investigational interleukin (IL)-36 receptor inhibitor could potentially add to the limited armamentarium of agents implemented within the GPP patient population.