Nedim Can Cevik

Keywords pancreatic cancer synapse glutamatergic receptor NMDAR L-glutamate GRIN2D neural invasion innervation Introduction Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy, ranking among the primary contributors to tumor-associated mortality worldwide.1,2,3,4,5,6,7 Human PDAC demonstrates an exceptionally high incidence of neural invasion (NI) and neuroplastic alterations.8,9,10,11 Cancer cells infiltrating nerves exploit them as conduits for dissemination, resulting in...