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Nicholas White on Muck Rack

Nicholas White

Covington
As seen in: Nature, PLOS, PLOS Medicine, American Express Business Trends and Insights, Yahoo, The Lancet, Cell Press, CSIRO Publishing, American Society for Microbiology (ASM), ASM Journals and

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Nicholas White’s Journalist Portfolio

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Articles

A dynamic pharmacometric framework defining the relationship between ivermectin exposure and mosquito lethality

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By Richard M. Hoglund, Podjanee Jittamala, Borimas Hanboonkunupakarn, Patchara Sriwichai, Nicholas White, Nicholas Day, Joel Tarning, Narenrit Wamaket, Siriporn Phasomkusolsil
| Nature Verified
Abstract Ivermectin is used in the treatment of several neglected tropical diseases. Studies have shown that it effectively kills anopheline mosquitoes. However, the relationship between the pharmacokinetic properties and mosquito-lethal effects have not been described quantitatively. Pharmacokinetic properties and mosquito-lethal effects associated with a single oral administration of ivermectin were evaluated in two healthy volunteer trials in Thailand.
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Efficient targeting of human glial progenitor cells in vivo with engineered AAV vectors and glymphatic delivery

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By Evan J. Newbold, Jessica Danner, Nicholas White, William Borden, Steven J. Schanz, Devin Chandler-Militello, Xiaojie Li, Jose Cano Verified, John Mariani, Maiken Nedergaard, Abdellatif Benraiss, Steven Goldman Verified, Alexander Cona, Deniz Kesmen, Rajiv Snape, Abigail Iseson
| Nature Verified
Abstract Treatment of neurological diseases that involve oligodendrocytes or astrocytes would benefit from the selective delivery of viral vectors to their common parent, glial progenitor cells (GPCs). Here, we select adeno-associated virus (AAV) capsids with tropism for human GPCs and demonstrate efficient and widespread delivery of the resultant AAVs throughout the mouse brain through the glymphatic system.
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Intraoperative optimization of radiocephalic arteriovenous fistula surgery with contemporary techniques

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By Nicholas White, Ruth M.A. Bulder, Eduard P. de Winter
| Annals of Vascular Surgery Verified
Keywords Arteriovenous fistula hemodialysis vascular access AVF maturation radiocephalic AVF 1 Introduction Radiocephalic arteriovenous fistulas (RCAVFs) remain the vascular access of choice for dialysis patients [1,2]. These RCAVFs provide durable autologous access with limited occurrence of excessively high flow [1,2], hemodialysis-access induced ischemia [3], or aneurysm formation [4].
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