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Nicolas R. Barthélemy on Muck Rack

Nicolas R. Barthélemy

As seen in: Color Research & Application, Nature, Wiley Online Library, JAMA (The Journal of the American Medical Association), JAMA Network, Cell Press, Artistik Rezo
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Articles

Plasma eMTBR-tau243 and %p-tau217 for Biological Staging of Alzheimer Disease

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By Gemma Salvadó, Kanta Horie, Nicolas Barthelemy, Nicolas R. Barthélemy, Suzanne Schindler, Shorena Janelidze, Anna Orduña Dolado, Divya Bali, Richard Perrin, JOHN MORRIS, Brian Gordon, Erik Stomrud, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Jacob Vogel, Randall J. Bateman, Rik Ossenkoppele, Oskar Hansson, Tammie L. S. Benzinger
| JAMA Network Verified
Plasma eMTBR-tau243 and %p-tau217 for Biological Staging of Alzheimer Disease Supplement 1. eTable 1. Demographic Characteristics of Knight ADRC Participants eTable 3. Confusion Matrices of Plasma-Based Stages Against PET-Based Stages in Each Subsample eTable 4. Statistics PET-Based Stages vs Plasma-Based Stages eTable 5. Cross-Sectional Differences in AD Biomarkers in BioFINDER-2 eTable 6. Differences in Longitudinal Changes in AD Biomarkers in BioFINDER-2 eTable 7.
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Trajectories of plasma and CSF MTBR-tau243 and phosphorylated-tau species across the Alzheimer’s disease continuum

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By Lyduine E. Collij, Gemma Salvadó, Kanta Horie, Nicolas Barthelemy, Nicolas R. Barthélemy, Tobey J. Betthauser, Olof Strandberg, Ruben Smith, Sebastian Palmqvist, Suzanne Schindler, Rik Ossenkoppele, Shorena Janelidze, Niklas Mattsson-Carlgren, Randall J. Bateman, Oskar Hansson
| Nature Verified
Abstract To efficiently implement plasma and cerebrospinal fluid (CSF) biomarkers for staging and prognosis of Alzheimer disease (AD), we must understand their dynamics across disease progression. We analyzed participants from the Swedish BioFINDER-2 study with mass spectrometry measurements of plasma and CSF tau species, including eMTBR-tau243/MTBR-tau243 and phosphorylation occupancies (%p-tau). Disease duration was estimated using Aβ-PET and tau-PET with the SILA algorithm.
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Neurofilament Proteoforms in Amyotrophic Lateral Sclerosis Are Different in Cerebrospinal Fluid and Blood

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By John B Coulton, Yingxin He, Melissa M Budelier, Nicolas Barthelemy, Nicolas R. Barthélemy
| Wiley Online Library Verified
Neurofilaments (NFs) are key cytoskeletal proteins that regulate axon integrity.1 NFs are primarily expressed in neurons and are represented by three subunits: neurofilament light (NfL), neurofilament medium (NfM), and neurofilament heavy (NfH) that complex with α-internexin in the central nervous system (CNS) or peripherin in the peripheral nervous system (PNS).
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