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Articles by Ningning Chen
In vitro and in vivo evaluation of liposomes constructed with Rg3 as a cholesterol substitute for tumor therapy
Abstract Conventional cholesterol liposomes have poor stability, rapid clearance, and toxicity. This study used Rg3 to replace cholesterol for constructing curcumin-loaded liposomes (PCRL) and evaluated their potential for enhanced hepatocellular carcinoma therapy. Curcumin-loaded liposomes were prepared with Rg3 (PCRL) and cholesterol (PCCL) via thin-film hydration.
Endometrial thickness is not a risk factor for hypertensive disorders of pregnancy after IVF treatment in women with male-factor infertility
Abstract Background: The relationship between endometrial thickness and adverse pregnancy outcomes has garnered significant attention from researchers. The aim of this study was to investigates whether endometrial thickness (EMT) is a risk factor for hypertensive disorders of pregnancy (HDP) in women undergoing in vitro fertilization (IVF) due to male-factor infertility.
Chineseness and Affective Spatialities: New Chinese Migrants' (Dis)Orienting Experiences of Chinese Voluntary Associations in Singapore
N.2026. “Chineseness and Affective Spatialities: New Chinese Migrants' (dis)orienting Experiences of Chinese Voluntary Associations in Singapore.” Population, Space and Place32: e70273. Chen, https://doi.org/10.1002/psp.70273. Conflicts of Interest The author declares no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References 2006.
MemSAM-2.5D: overcoming volumetric discontinuity and boundary ambiguity for 3D liver tumor segmentation
Abstract Introduction: Accurate segmentation of liver tumors from 3D computed tomography (CT) volumes is essential for the clinical management of hepatocellular carcinoma (HCC), but remains challenging because of extreme lesion-scale variation, volumetric discontinuity across slices, and ambiguous tumor boundaries. Methods: We propose MemSAM-2.5D, a unified 2.5D segmentation framework built upon the MedSAM foundation model.
Distinctive genetic architecture of infantile epileptic spasms syndrome compared to self‐limited infantile epilepsy by trios whole‐exome sequencing
WES achieved 37% diagnostic yield in IESS and 95% in SeLIE, supporting first-line use for SeLIE. Ten novel pathogenic or likely pathogenic variants were discovered, with IESS showing higher de novo LoF variant burden. 51.9% of IESS patients responded to initial hormonal therapy. IESS displayed high genetic heterogeneity with 17 distinct causal genes identified.
Educational expansion and economic development: do they necessarily promote gender employment equity? Evidence from job satisfaction in Chinese universities
ABSTRACT The expansion of higher education and economic development is widely believed to improve gender employment equity by enhancing women’s access to education and skills. However, recent studies suggest these benefits may not extend universally, particularly regarding subjective well-being, where women often face new challenges amid educational and economic transitions.
Consciousness trajectories and functional independence after acute brain injury in children with prolonged disorder of consciousness
Figure S1: Flow chart for patient selection to perform consciousness and living functional independence analysis. Figure S3: The least absolute shrinkage and selection operator (LASSO) regression in the logistic model. Figure S4: The proportion curve of all children with unfavourable functional living independence. Table S2: Aetiologies and demographic detail information of the original cohort. Table S3: Demographic and basic characteristics of the anoxic group.
The Effect of Job Skill Demands under Artificial Intelligence Embeddedness on Employees’ Job Performance: A Moderated Double-Edged Sword Model
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Effect of Zn on Microstructure and Wear Resistance of Sn-Based Babbitt Alloy
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Effect of Rare Earth Y on the Microstructure, Mechanical Properties and Friction of Sn-Babbitt Alloy
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Monolithically integrated four-channel laser array based on high-order surface gratings for O-band CWDM systems
An O-band monolithically integrated four-channel laser array based on high-order surface gratings is demonstrated. The fabricated laser array exhibits a wide bandwidth of up to 60 nm, with threshold currents ranging from 17 to 25 mA and slope efficiencies between 0.22 and 0.29 W/A. At an injection current of 200 mA, all side-mode suppression ratios (SMSRs) are above 40 dB, and the output power exceeds 36 mW.
A Method to Facilitate the Regeneration of Human Resources: A Sustainability Perspective
1. Introduction Guided by the traditional emphasis on economic efficiency, organizations have historically favored cost-minimization strategies when deploying and planning their human resources, such as the preference for reuse over development [,,,], at the expense of their resource bases’ stability and sustainability [].
Diasporic Chinese voluntary associations engage China's rise
Conflict of interest There are no potential conflicts of interest. References (2020) Rural community unbound: Translocality, rural-to-rural connections and the formation of inter-regional surname associations in China, Journal of Rural Studies 78: 378–386. and (2023) Diaspora governance and religion: The (re)production of the Guangze Zunwang cult in the Chinese diaspora, Global Networks 23(3): 583–598. , and (2023) Beyond migration?
Massive underrepresentation of Arabs in genomic studies of common disease - Genome Medicine
Discoveries from GWAS have begun to move into the clinical space through implementation of polygenic risk scores (PRS). It is now well-established that lack of diversity in reference genomes and published GWAS limit portability and accuracy of PRS prediction in non-European ancestries.
Research on Three-Dimensional Shape Curve Reconstruction Technology for a Scraper Conveyor on an Intelligent Working Face
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Clinical utility of polygenic scores for cardiometabolic disease in Arabs - Nature Communications
Abstract Arabs account for 5% of the world population and have a high burden of cardiometabolic disease, yet clinical utility of polygenic risk prediction in Arabs remains understudied. Among 5399 Arab patients, we optimize polygenic scores for 10 cardiometabolic traits, achieving a performance that is better than published scores and on par with performance in European-ancestry individuals.
Research on the Three-Machines Perception System and Information Fusion Technology for Intelligent Work Faces
2. Intelligent Perception System for Three-Machines Status 2.1. Optical Fiber Sensor Fiber optic sensing technology has the advantages of high accuracy and strong anti-interference ability. After reasonable packaging, it can achieve strong environmental tolerance, and the networking methods are flexible and diverse [32,33]. After proposing the unmanned working face mining technology system, Fang et al.
Caching Placement Optimization Strategy Based on Comprehensive Utility in Edge Computing
5.3. Experimental Results and Analysis Impact of different cache sizes on the algorithmic performance To evaluate the impact of different cache capacities on the algorithm’s performance, the cache capacity of each server was set to vary between 30 and 60 data blocks. A total of 200 tasks were simulated to be executed by users. The impact of different cache capacities on the cache service rate generated by the four algorithms is shown in Figure 4.
Geographical articulations of rurality at the rural‐urban interface
Research on the intermediate space or interface where rural and urban boundaries become blurred has been gaining momentum within geography and other intersecting fields. In contrast to the dominant focus on the growth of urbanism at the rural-urban interface, a growing number of studies have emerged to intervene the debate from the rural side.
Functional Characterization of a New Salt Stress Response Gene, PeCBL4, in Populus euphratica Oliv
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Vaccination against COVID‐19 and potential protective effects on seizure recurrence in children with epilepsy : A cross‐sectional survey
ORIGINAL ARTICLE This article has been accepted for publication and undergone full peer review but has not been through the copyediting, typesetting, pagination and proofreading process, which may lead to differences between this version and the Version of Record. Please cite this article as doi:10.1002/epi4.12794.
A process calculus SMrCaIT for IoT
REFERENCES 1. Technology framework of the Internet of Things and its application. In: 2011 International Conference on Electrical and Control Engineering. IEEE; 2011: 4109-4112. 2, , , . Recent security trends in Internet of Things: a comprehensive survey. IEEE Access. 2021; 9: 113292-113314. doi:10.1109/ACCESS.2021.3103725 3, , , . Internet of Things: vision, applications and research challenges. Ad Hoc Netw. 2012; 10(7): 1497-1516. 4, , , et al.
Articulating relational rurality amidst urbanization: Agency, spatial paradox and the de/reterritorialization of lineage landscapes in contemporary rural China
REFERENCES , & (2014) New spaces for nature: The re-territorialisation of biodiversity conservation under neoliberalism in the UK. Transactions of the Institute of British Geographers, 39, 574–588. Available from: https://doi.org/10.1111/tran.12050 (2004) The corporeal politics of quality (suzhi). Public Culture, 16, 189–208. Available from: https://doi.org/10.1215/08992363-16-2-189 , , & (2012) On assemblages and geography. Dialogues in Human Geography, 2, 171–189.
Predicting the antigenic evolution of SARS-COV-2 with deep learning - Nature Communications
Dataset We collected and cleaned nine deep mutational scanning datasets, which measure the binding affinity of the SARS-COV-2 RBD variants towards the ACE2 and eight antibodies from four classes. We built a dataset consisting of 19132 RBD sequences, where each sequence has nine labels, corresponding to their binding ability to the nine targets. Most sequences have one or two mutations compared to the wild-type RBD sequence.
Beyond migration? Alternative articulations of transnational religious networks
DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request.
Simulation Optimization and Application of Shearer Strapdown Inertial Navigation System Modulation Scheme
Abstract : The operating attitude of a shearer based on a three-dimensional (3D) space scale is the necessary basic information for realizing intelligent mining. Aiming to address the problem of the insufficient perception accuracy of shearers, in this paper, the rotation model of the actual turning mechanism of the strapdown inertial navigation system (SINS) of shearers is established, and the error propagation characteristics of different single-axis rotation modulation schemes are revealed.
Efficient K‐Storage of Fe‐Coupled Organic Molecule Anode in Ether‐Based Electrolytes
Graphical Abstract Metal coupling strategy combined with electrolytes regulation are adopted to develop a novel organic K-storage anode of Fe-NTCDA with improved specific capacity and long cycle stability in the optimized 3 M KFSI/DME electrolytes, attributed to the increased K-storage sites as well as enhanced K+ transfer kinetics.
PtoNF-YC9-SRMT-PtoRD26 module regulates the high saline tolerance of a triploid poplar - Genome Biology
Plant materials and treatments The triploid Chinese white poplar cuttings were propagated by tissue culture using woody plant medium (WPM) supplemented with 0.1 mg/L naphthylacetic acid (NAA) at 25 °C with a 14 h / 10 h light / dark photoperiod (4500 lux). The rooted plantlets were transplanted into soil in the greenhouse at 25 °C and 16 h / 8 h light / dark cycle.
Bioinformatics analysis integrating metabolomics of m6A RNA microarray in intervertebral disc degeneration
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Strain transferring mechanism analysis of the surface-bonded FBG sensor
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Effects of dietary protein and fiber at breakfast on postprandial appetite, neural responses to visual food stimuli, and ad libitum energy intake at lunch in overweight adults
Increasing either protein or fiber at mealtimes has relatively modest effects on satiety and ingestive behavior. Whether increasing protein and fiber in the same meal has additive or interactive effects on ingestive behavior is not known.
Higher-protein diets improve indexes of sleep in energy-restricted overweight and obese adults: results from 2 randomized controlled trials
↵ 1 Supported by The Beef Checkoff (study 1), the National Pork Board (study 1), the National Dairy Council (study 2), the Purdue Ingestive Behavior Research Center (study 2), and the NIH (grant UL1TR001108; studies 1 and 2). Background: Limited and inconsistent research findings exist about the effect of dietary protein intake on indexes of sleep.
Dietary Approaches to Stop Hypertension diet retains effectiveness to reduce blood pressure when lean pork is substituted for chicken and fish as the predominant source of protein
↵ 1 Supported by the National Pork Board, the NIH Indiana Clinical and Translational Sciences Institute, Clinical Research Center (grant UL1TR001108), and the USDA (2011-38420-20038). Background: Hypertension is a major, modifiable risk factor for cardiovascular and kidney disease and premature mortality that is improved by the DASH (Dietary Approaches to Stop Hypertension) diet.
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