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Articles by Patricia Stapleton
Harnessing the Power of Science and Technology Communities for Crisis Response
The U.S. Department of Homeland Security (DHS) has to respond to crises generated by a variety of threats and hazards, such as natural disasters, terrorist attacks, and public health emergencies. When confronted with such challenges in the past, DHS has relied on scientific and technical advice and solutions to identify gaps in its processes and operations.
Elections and compulsory photo ID – what effect will it have on Gypsies and Irish Travellers? - EachOther
At the annual Queen’s Speech last week, the controversial Electoral Integrity Bill was announced. If passed, it means that voters will need to produce a valid form of photo ID when they cast their vote. The government rationale behind the legislation is to secure trust and prevent fraud in UK voting systems. It is thought the legislation will be in place by next year.
Small Protein, Big Breakthrough for CRISPR Gene Editing
Move over CRISPR Cas9, here comes CasΦ, a small but mighty new gene editing protein. The discovery of CRISPR Cas9, the most widely used CRISPR gene editing system, made huge waves in medicine and biotech over the last decade. It's hard to imagine anything surpassing it, but CasΦ (pronounced "Cas-phi") could be another game-changer. The CRISPR gene editing proteins, or Cas proteins, are DNA "scissors" naturally found in bacteria and archaea.
Gene Writing: A New Type of Genetic Engineering
After years of hype as a potentially transformative technology, CRISPR is finally starting to make good on its promise for treating genetic disorders — even curing a handful of patients of sickle cell disease. But even at its best, CRISPR has problems. It’s far better at deleting broken genes than inserting replacements, which limits the kinds of diseases it can treat.
Gene Therapy Hailed as Cure for Sickle Cell Disease
Last year researchers in the U.S. began testing the ability of CRISPR, a technology that can edit the DNA of living cells, to potentially treat or even cure genetic diseases in humans. This week, one group announced promising results from an on-going clinical trial that suggests CRISPR may deliver a much-needed cure for sickle cell disease and beta thalassemia — two of the most common genetic disorders in the world.
Gene Editing Corrects Deafness-Causing Mutation in Mice
The inner ear houses at least 100 hearing-related genes — and a single mutation in just one of them can lead to hearing loss. Now, using a cutting-edge technique for gene editing, researchers have corrected a deafness-causing genetic mutation in mice — partially restoring the animals' ability to hear. Gene Editing to Alleviate Deafness In humans, every gene is composed of a specific sequence of paired off DNA bases (A, G, T, or C).
Genetically Engineering the First Hypoallergenic Cat
For the 10% of people with cat allergies, a run-in with a kitten can mean anything from slightly itchy eyes to life-threatening anaphylaxis. In an attempt to still enjoy feline companionship, some of those people think it's a good idea to buy a hypoallergenic cat — one whose biology won't trigger their allergies — as a pet. The only problem? Despite what breeders of Sphynx and Cornish Rex kittens might say, there is no such thing as a hypoallergenic cat — not yet, anyways.
CRISPR Virus Detection Tool Can Test for 169 Viruses at Once
For doctors, it's often easy to tell if a patient is sick — they're coughing, feverish, and feel like hell — but knowing what's making them sick can be far trickier, requiring a bevy of time-consuming diagnostic tests. Now, a team of researchers from the Broad Institute has created a virus detection tool that can test for nearly all viruses that commonly infect humans, at once, delivering same-day results.
“Politics of Plague” Course Materials
Thanks to Dr. Laurel Eckhouse for putting together a list of poli sci scholars who have offered to guest lecture if/when needed! I’ve noted that I’ve developed and taught a course called the “Politics of Plague” that might be of use to others. You can find the course syllabus here. I’m most proud of the intro activity to the course that I developed for the first day of class to get students engaged in the ideas.
Patricia Joan Stapleton
Patricia Joan Stapleton Mrs. Patricia Joan Stapleton, age 75, of Kerrville, passed away Sunday afternoon, Dec. 8, 2019, at her residence at Riverview Nursing Home, Boerne, Texas. A celebration of life service will be held at 4:30 p.m., Monday, Dec. 23, 2019, at Grimes Funeral Chapels, 728 Jefferson St., Kerrville. She was born March 26, 1944, in Anaheim, Calif., the daughter of the late John and Linda Hushman.
Guide on supporting Gypsy, Roma and Traveller pupils
Pupils from Gypsy, Roma and Traveller backgrounds have the lowest school attainment of all ethnic groups, says Patricia Stapleton. School leaders can help to change that June is Gypsy, Roma and Traveller history month, which celebrates the culture and heritage of GRT communities and is therefore a timely moment to highlight the needs of children from these communities within education.
As I See It: Public's interest is crucial in gene-editing discussion
By Patricia A. Stapleton Wednesday Dec 19, 2018 at 3:01 AM The recent disclosure that Chinese scientist He Jiankui had created the world’s first genetically-edited babies roiled the scientific community on the eve of the Second International Summit on Human Genome Editing.
Scared of CRISPR? 40 years on, IVF shows how fears of new medical technology can fade
The first “test-tube baby” made headlines around the world in 1978, setting off intense debate on the ethics of researching human embryos and reproductive technologies. Every breakthrough since then has raised the same questions about “designer babies” and “playing God” – but public response has grown more subdued rather than more engaged as assisted reproductive technologies have become increasingly sophisticated and powerful.
Scared of CRISPR? 40 years on, IVF shows how fears of new medical technology can fade
The first “test-tube baby” made headlines around the world in 1978, setting off intense debate on the ethics of researching human embryos and reproductive technologies. Every breakthrough since then has raised the same questions about “designer babies” and “playing God” — but public response has grown more subdued rather than more engaged as assisted reproductive technologies have become increasingly sophisticated and powerful.
Scared of CRISPR? 40 Years Ago, People Felt The Same About IVF
The first "test-tube baby" made headlines around the world in 1978, setting off intense debate on the ethics of researching human embryos and reproductive technologies. Every breakthrough since then has raised the same questions about "designer babies" and "playing God" – but public response has grown more subdued rather than more engaged as assisted reproductive technologies have become increasingly sophisticated and powerful.
Scared of CRISPR? 40 years on, IVF shows how fears of new medical technology can fade
The first “test-tube baby” made headlines around the world in 1978, setting off intense debate on the ethics of researching human embryos and reproductive technologies. Every breakthrough since then has raised the same questions about “designer babies” and “playing God” – but public response has grown more subdued rather than more engaged as assisted reproductive technologies have become increasingly sophisticated and powerful.
As I See It: Major storms & climate change: Rethinking our approach to the elephant in the room
By Patricia Stapleton Hurricane Irma made landfall in southern Florida as a Category 4 storm on September 10th. As Irma worked up the middle of the state, rain, wind, and floods left more than 6 million residents without power and caused $70 billion to $90 billion in economic damage.
Will the public embrace CRISPR to 'edit out' birth defects as it has other reproductive technologies? | Genetic Literacy Project
The first “test-tube baby” made headlines around the world in 1978, setting off intense debate on the ethics of researching human embryos and reproductive technologies. Every breakthrough since then has raised the same questions about “designer babies” and “playing God” – but public response has grown more subdued rather than more engaged as assisted reproductive technologies have become increasingly sophisticated and powerful.
Viewpoint: Will CRISPR fears fade with familiarity the way they did for 'test-tube babies' - Boston Business Journal
The first "test-tube baby" made headlines around the world in 1978, setting off intense debate on the ethics of researching human embryos and reproductive technologies. Every breakthrough since then has raised the same questions about " designer babies" and " playing God" - but public response has grown more subdued rather than more engaged as assisted reproductive technologies have become increasingly sophisticated and powerful.
Will CRISPR Fears Fade With Familiarity?
The first “test-tube baby” made headlines around the world in 1978, setting off intense debate on the ethics of researching human embryos and reproductive technologies. Every breakthrough since then has raised the same questions about “designer babies” and “playing God” – but public response has grown more subdued rather than more engaged as assisted reproductive technologies have become increasingly sophisticated and powerful.
Will CRISPR fears fade with familiarity?
As the science has advanced, doctors are able to perform more complex procedures with better-than-ever success rates. This progress has made in vitro fertilization and associated assisted reproductive technologies relatively commonplace. Over one million babies have been born in the U.S. using IVF since 1985. And Americans' acceptance of these technologies has evolved alongside their increased usage, as we've gotten used to the idea of physicians manipulating embryos.
Will CRISPR fears fade with familiarity?
The first “test-tube baby” made headlines around the world in 1978, setting off intense debate on the ethics of researching human embryos and reproductive technologies. Every breakthrough since then has raised the same questions about “designer babies” and “playing God” – but public response has grown more subdued rather than more engaged as assisted reproductive technologies have become increasingly sophisticated and powerful.
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