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Paul Kaye

Toronto, Vancouver
As seen in: LinkedIn, Nature, Adoro Cinema, Télé Loisirs, Cell Press, FormulaTV, JustWatch, All Access, Derbyshire Life, The Media Online and
VP @Rogers. Champion of content, coaching, leadership & creative cultures.paulkaye.co
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Articles

Lymphocyte-mediated immune responses to Leishmania infection

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By Christian Engwerda, Paul Kaye, Simona Stäger
| Nature Verified
Abstract Leishmania are intracellular protozoan parasites transmitted to humans by the bite of infected phlebotomine sand flies. Human infection is often asymptomatic but can develop into a broad spectrum of clinical diseases, collectively termed the leishmaniases.
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Ontogeny independent expression of LPCAT2 in granuloma macrophages during experimental visceral leishmaniasis

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By Shoumit Dey, Jian-Hua Cao, Benjamin Balluff, Helen Ashwin, Lesley Gilbert, Sally James, Adam Dowle, Grant Calder, Nidhi Sharma Dey, Peter O’Toole, Ron Heeren, Paul Kaye, Gaia Mazza
| Nature Verified
Abstract Granulomas are organized inflammatory lesions formed in response to persistent stimuli such as infections. Murine infection with Leishmania donovani results in granulomas in the liver, seeded by infected Kupffer cells, and serves as a well-defined model of infection-induced granuloma formation. The resolution of granulomatous inflammation requires dynamic shifts in immune-cell activation states, imposing metabolic demands.
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Breaking the deadlock in antigen discovery for Leishmania vaccines

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By Wim Adriaensen, Nicky de Vrij, Thao-Thy Pham, Kris Laukens, Pieter Meysman, Paul Kaye
| Cell Press Verified
Keywords vaccine leishmaniasis Leishmania antigen discovery Get full text access Log in, subscribe or purchase for full access. References 1. World Health Organization Global leishmaniasis surveillance: 2019–2020, a baseline for the 2030 roadmap Wkly Epidemiol. Rec. 2021; 35:401-419 2. Pareyn, M. ... Leishmaniasis Nat. Rev. Dis. Primers. 2025; 11:81 3. Kaye, P.M. ... Vaccine value profile for leishmaniasis Vaccine. 2023; 41:S153-S175 4. Nylen, S. ∙ Gautam, S. Immunological perspectives of leishmaniasis J.
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