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Sally James

As seen in: MSN UK, Nature, Columns Magazine, Science Magazine, BioRxiv, AOL UK, School Library Journal, Parent Map, Mondaq, SeafoodSource.com
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Articles

Bi-directional highways and super-seeder tissues underpin parasite dissemination in experimental Leishmania donovani infection

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By Shoumit Dey, Helen Ashwin, Sally James, Lesley Gilbert, Alastair Droop, Grant Calder, Karen Hogg, Jon Pitchford, Jeremy C. Mottram, Paul Kaye, Ciara Loughrey, Juliana B. T. Carnielli, Samantha Donninger
| Nature Verified
Abstract Visceral leishmaniasis (VL) is a life-threatening parasitic disease caused by Leishmania donovani and L. infantum. Although VL is characterised by organ-specific immunopathology and parasitism of the spleen, liver and bone marrow, other tissues may harbour parasites without overt pathology. The mechanisms governing patterns of within-host dissemination and tissue tropism are largely unknown. Here, we use a barcoded library of isogenic L.
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Dolly Parton revealed what she wanted her legacy to be months before her death

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By Daniel Bird Verified, Sally James
| AOL UK Verified
Tue, August 25, 2026 at 9:18 PM UTC Dolly wanted to be remembered as a 'normal person' -Credit:Getty Images Dolly Parton revealed she wanted to be remembered as a "normal person" as her final wish. The country icon has died, aged 80, following months of health setbacks. But speaking earlier this year, the musician, who was one of the most celebrated in history, revealed how, despite being a larger-than-life character from Pittman Center, Tennessee, she had simply "got lucky".
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Ontogeny independent expression of LPCAT2 in granuloma macrophages during experimental visceral leishmaniasis

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By Shoumit Dey, Jian-Hua Cao, Benjamin Balluff, Helen Ashwin, Lesley Gilbert, Sally James, Adam Dowle, Grant Calder, Nidhi Sharma Dey, Peter O’Toole, Ron Heeren, Paul Kaye, Gaia Mazza
| Nature Verified
Abstract Granulomas are organized inflammatory lesions formed in response to persistent stimuli such as infections. Murine infection with Leishmania donovani results in granulomas in the liver, seeded by infected Kupffer cells, and serves as a well-defined model of infection-induced granuloma formation. The resolution of granulomatous inflammation requires dynamic shifts in immune-cell activation states, imposing metabolic demands.
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