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Paul W. Barone on Muck Rack

Paul W. Barone

Boston
As seen in: Nature, BioRxiv, Cell Press, Chemical Engineering Progress, BioPharm International
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Articles

An Integrated Experimental and Modeling Approach for Crystallization of Complex Biotherapeutics

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By Vivekananda Bal, Jacqueline Wolfrum, Paul W. Barone, Stacy Springs
| dx.doi.org
Special Issue Published as part of Crystal Growth & Design special issue “Design of Crystals via Crystallization Processes”. 1. Introduction Click to copy section linkSection link copied! Protein crystallization is important in the field of bioscience and biotechnology research as it has numerous applications including protein purification, low-viscosity drug substance and drug product formulation, drug discovery, and target identification and selection.
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Machine-learning based detection of adventitious microbes in T-cell therapy cultures using long read sequencing

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By Elizabeth Lee, Paul W. Barone, James P.B. Strutt, Meenubharathi Natarajan
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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Mechanistic model for production of recombinant adeno-associated virus via triple transfection of HEK293 cells

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By Byrne B.J, Tam Nguyen, Tâm Nguyễn, Andrew Maloney Verified, Paul W. Barone
| Cell Press Verified
Recombinant adeno-associated virus (rAAV) is the replication-incompetent form of the wild-type parvovirus AAV and is employed for in vivo gene-therapy treatments. Its reduced toxicity, robust and long-term transgene expression, and ability to transduce both dividing and non-dividing cells as well as target a wide range of tissues has made rAAV the most widely used viral vector.
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