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Articles by Peter Devilee
Toepasselijk einde
Terug naar de krant Ik hou erg van afspeellijstjes met een inspirerend thema, dus las met veel plezier Wat zijn de 21 mooiste ‘wintersongs’? (21/12). Daarvan zijn er meerdere te vinden op Spotify, maar de NRC-lijst moest ik zelf samenstellen (staat online, zonder verwijzing op papier, red.). Ik heb ’m wel laten eindigen met ‘Spring Will Be A Little Late This Year’ van Sarah Vaughn, leek me wel toepasselijk met de verkiezingsuitslag in gedachten.
Author Correction: Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk | Nature Genetics
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Correction to: Nature Genetics https://doi.org/10.1038/s41588-023-01466-z, published online 17 August 2023. In the version of the article initially published, in the sentence in the Abstract now reading “Associations were also observed for LZTR1, ATRIP and BARD1 with P < 1 × 10−4”, “ATRIP” appeared incorrectly as “ATR”. This has now been corrected in the PDF and HTML versions of the article.
By Eugene J. Gardner, Heiko Becher, Sabine Behrens, Thilo Dörk, Pascal Guénel, SGBCC Investigators, Jingmei Li, Michael Lush, Kyriaki Michailidou, Mihalis I Panayiotidis, Xueling Sim, Soo Hwang Teo, Jonathan P Tyrer, Qin Wang, Marjanka K. Schmidt, Alison Dunning, Anders Kvist, Peter Devilee, Douglas F. Easton
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Nature
Verified
Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk - Nature Genetics
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Abstract Linkage and candidate gene studies have identified several breast cancer susceptibility genes, but the overall contribution of coding variation to breast cancer is unclear. To evaluate the role of rare coding variants more comprehensively, we performed a meta-analysis across three large whole-exome sequencing datasets, containing 26,368 female cases and 217,673 female controls.
By Eugene J. Gardner, Heiko Becher, Sabine Behrens, Thilo Dörk, Pascal Guénel, Jingmei Li, Michael Lush, Kyriaki Michailidou, Mihalis I Panayiotidis, Xueling Sim, Soo Hwang Teo, Jonathan P Tyrer, Qin Wang, Marjanka K. Schmidt, Alison Dunning, Anders Kvist, Peter Devilee, Douglas F. Easton, SGBCC Investigators
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Nature
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PREDICT validity for prognosis of breast cancer patients with pathogenic BRCA1/2 variants - npj Breast Cancer
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Abstract We assessed the PREDICT v 2.2 for prognosis of breast cancer patients with pathogenic germline BRCA1 and BRCA2 variants, using follow-up data from 5453 BRCA1/2 carriers from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA) and the Breast Cancer Association Consortium (BCAC).
By Taru A. Muranen, Sofia Khan, Joe Dennis, Renske Keeman, Goska Leslie, Michael Parsons, Thomas Ahearn, Irene L. Andrulis, Sabine Behrens, Peter Devilee, D. Gareth Evans, Montserrat Garcia-Closas, Louise Izatt, Anna Jakubowska, Paul James, Geoffrey J Lindeman, Susan Neuhausen, William Newman, Paolo Peterlongo, Emmanouil Saloustros, Maija Suvanto, Manuel R. Teixeira, Douglas F. Easton, Marjanka K. Schmidt
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Nature
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FANCM missense variants and breast cancer risk: a case-control association study of 75,156 European women - European Journal of Human Genetics
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Abstract Evidence from literature, including the BRIDGES study, indicates that germline protein truncating variants (PTVs) in FANCM confer moderately increased risk of ER-negative and triple-negative breast cancer (TNBC), especially for women with a family history of the disease. Association between FANCM missense variants (MVs) and breast cancer risk has been postulated.
By Gisella Figlioli, Heiko Becher, Sabine Behrens, Marinus J. Blok, Bernardo Bonanni, Stephen J. Chanock, Peter Devilee, Thilo Dörk, Felix Grassmann, Antoinette Hollestelle, K ConFab Investigators, Anna Jakubowska, Jolanta Lissowska, William Newman, Mihalis I Panayiotidis, Muhammad Rashid, Xiaohong Yang, Joe Dennis, Douglas F. Easton, Kyriaki Michailidou, Marjanka K. Schmidt, Irene L. Andrulis, Heli Nevanlinna, Roger Milne, Paolo Radice, NBCS Collaborators, Emmanouil Saloustros
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Nature
Verified
Patient Power
Mutations in genes BRCA1 and BRCA2 are important risk factors for developing breast cancer. But other factors such as the number of children, obesity and breast density can also influence the development of the disease. Professor Peter Devilee, geneticist at Leiden University Medical Centre, explains the genetics and other lifestyle risk factors that can influence breast cancer.
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