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Phillip Chapman

As seen in: BBC News, BioRxiv, Cell Press, Fort Collins Coloradoan, Post-Bulletin, Cranleigh Magazine
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Articles

A brain-wide map of descending inputs onto spinal V1 interneurons

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By Phillip Chapman, Anand Kulkarni, Alexandra J. Trevisan, Katie Han, Jennifer Hinton, Paulina Deltuvaite, Lief Fenno, Charu Ramakrishnan, Mary Patton, Lindsay A. Schwarz, Stanislav S. Zakharenko, Karl Deisseroth, Jay B. Bikoff
| Cell Press Verified
Keywords motor system neural circuits spinal cord interneurons connectivity viral tracing whole-brain map supraspinal pathways monosynaptic rabies virus Introduction Movement emerges from the coordinated activity of neuronal populations distributed across multiple regions of the nervous system. This motor infrastructure spans an array of supraspinal structures, including cortical, basal ganglia, brainstem, and cerebellar systems.
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The transcriptomic landscape of spinal V1 interneurons reveals a role for En1 in specific elements of motor output

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By Alexandra J. Trevisan, Katie Han, Phillip Chapman, Anand Kulkarni
| BioRxiv
Abstract Neural circuits in the spinal cord are composed of diverse sets of interneurons that play crucial roles in shaping motor output. Despite progress in revealing the cellular architecture of the spinal cord, the extent of cell type heterogeneity within interneuron populations remains unclear. Here, we present a single-nucleus transcriptomic atlas of spinal V1 interneurons across postnatal development.
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Harrogate pianist with dementia finds fame with love song for wife Original

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By Phillip Chapman
| BBC Verified
Pianist with dementia finds fame with song for wife By Phillip Chapman, Rachel Russell, BBC News BBC Duncan Goodwin dedicated his composition to his wife Fran A pianist with dementia who reached the final of Channel 4's The Piano said he had "never been happier" following his appearance on the show. Duncan Goodwin, 81, from Harrogate, hoped to raise awareness of the illness by performing in the TV contest.
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