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Pradeep Singh Cheema

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Articles

PARP1 suppression drives ROS resistance in aneuploid cancer cells

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By Pan Cheng, Angela Mermerian-Baghdassarian, Yufeng Wang, Ze Chen, Helberth Quysbertf, Pradeep Singh Cheema, Joseph C. Mays, Xin Zhao, Lizabeth Katsnelson, Sally Mei, Rohini Shrivastava, Mirna Bulatovic, Jiehui Deng, Markus Schober, Kwok-Kin Wong, Teresa Davoli
| Cell Press Verified
Keywords aneuploidy cancer PARP1 oxidative stress cell death Introduction Aneuploidy, a hallmark of cancer,1 correlates with tumor progression, poor survival, and therapeutic resistance.2,3,4 The role of aneuploidy in cancer, however, remains incompletely understood.
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