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Rajiv C. McCoy on Muck Rack

Rajiv C. McCoy

Baltimore, Seattle
As seen in: Nature, PNAS, The Conversation, Genome Biology, Science Magazine, BioRxiv
Associate professor at Johns Hopkins studying human evolutionary and reproductive genetics
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Articles

Assembling unmapped reads reveals hidden variation in South Asian genomes

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By Arun Das Verified, Arjun Biddanda, Rajiv C. McCoy, Michael C Schatz
| Nature Verified
Abstract Conventional genome mapping-based approaches systematically overlook genetic variation, particularly in regions that substantially differ from the reference. To explore this hidden variation, here we examine unmapped and poorly mapped reads from the genomes of 640 human individuals from South Asian populations in the 1000 Genomes Project and the Simons Genome Diversity Project.
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Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair - Scientific Data

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By Jennifer McDaniel, Vaidehi Patel, Nathan Olson, Hua-Jun He, Zhiyong He, Kristin Sikkink, Fritz J Sedlazeck, Harsha V. Doddapaneni, Shalini N. Jhangiani, Marie-Claude Gingras, Heer H. Mehta, Sairam Behera, Luis F. Paulin, Victor Weigman, Isai Salas-Gonzalez, Miten Jain, Giuseppe Narzisi, Catherine Reeves, Aaron M. Wenger, Ian McLaughlin, Benedict Paten, Jimin Park, Karen H Miga, Joshua Gardner, Gail Rosen, Rajiv C. McCoy, Francesco Brundu, Konrad Scheffler, Sean Truong, Severine Catreux, Lesley Hannah, Nika Iremadze, Mikhail Kolmogorov, Ayse G. Keskus, Asher Bryant, Christopher Mason, Justin P. Wagner, Andrew Liss, Alison Rojas, Mitch Sudkamp, Erfan Sayyari, Chunlin Xiao
| Nature Verified
Abstract The Genome in a Bottle Consortium (GIAB), hosted by the National Institute of Standards and Technology (NIST), is developing new matched tumor-normal samples, the first explicitly consented for public dissemination of genomic data and cell lines.
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Chromosomal instability in human trophoblast stem cells and placentas - Nature Communications

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By Stephen A. MCCARTNEY, Ian Glass, Rajiv C. McCoy
| Nature Verified
Abstract The human placenta, a unique tumor-like organ, is thought to exhibit rare aneuploidy associated with adverse pregnancy outcomes. Discrepancies in reported aneuploidy prevalence in placentas stem from limitations in modeling and detection methods.
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