Richard Barfield

Editor’s summary To test whether a therapeutic approach for HIV infection could be curative, people living with HIV need to undergo an analytical treatment interruption (ATI) where they stop taking antiretroviral therapy (ART). Although adults can volunteer for such studies, they are ethically tricky to conduct in pediatric populations. Here, Obregon-Perko et al. asked whether a preclinical pediatric nonhuman primate model might offer insights into features associated with viral control.

Editor’s summary Congenital cytomegalovirus (cCMV) infections are a major driver of birth defects and neurodevelopmental delays in human newborns. Thus, strategies to prevent transplacental mother-to-fetus transmission are urgently needed. One proposed strategy is to vaccinate against the viral pentameric complex (PC), a multiglycoprotein complex required for viral entry into nonfibroblast cells in tissue culture. Here, Wang et al.

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