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Articles by Robb Rowley
Additive value of polygenic risk and family history for coronary heart disease risk stratification in two diverse US cohorts
Keywords polygenic risk score family history coronary heart disease risk prediction risk reclassification prevention coronary artery disease risk assessment Get full text access Log in, subscribe or purchase for full access. References 1. GBD 2021 Forecasting Collaborators Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021 Lancet. 2024; 403:2204-2256 2.
Navigating data sharing in research
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PerspectiveOnline nowOpen access Affiliations & Notes 1Department of Medicine, Brigham and Women’s Hospital, Boston, MA, USA 2Harvard Medical School, Boston, MA, USA 3Center for Biomedical Ethics and Society, Vanderbilt University Medical Center, Nashville, TN, USA 4Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA 5Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, USA 6Institute for Genomic Health, Icahn School of Medicine at...
By Anna Lewis, Ellen Clayton, Hana Bangash, Harris T. Bland, Katherine E. Bonini, James Cimino, John Connolly, Robert R. Freimuth, Stephanie M. Fullerton, Hakon Hakonarson, Ingrid A. Holm, Gail P. Jarvik, Atlas Khan, Krzysztof Kiryluk, Jodell E. Linder, Yuan Luo, John Lynch, Kathleen F. Mittendorf, Jennifer Pacheco, Luke V. Rasmussen, Susannah L. Rose, Robb Rowley, Richard Sharp, Theresa L. Walunas, Wei-Qi Wei, Chunhua Weng, Maya Sabatello
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The American Journal of Human Genetics
Verified
Genomic medicine year in review: 2024
1National Human Genome Research Institute, National Institutes of Health, Bethesda, MD 20892, USA 2The Jackson Laboratory for Mammalian Genetics, Bar Harbor, ME 04609, USA 3Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA 4All of Us Research Program, National Institutes of Health, Bethesda, MD 20892, USA 5Concert, Nashville, TN 37201, USA 6Departments of Medicine (Medical Genetics) and Genome Sciences, University of Washington, Seattle,...
The PRIMED Consortium: Reducing disparities in polygenic risk assessment
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Keywords polygenic risk score equity diversity Introduction As genomic technologies spur progress in several areas of precision medicine, inequity in translating these advances to diverse groups has become evident.
By Iftikhar J. Kullo, Matthew P. Conomos, Sally N. Adebamowo, Ananyo Choudhury, Stephanie Fullerton, Stephanie M Gogarten, Ben Heavner, Whitney E. Hornsby, Eimear E. Kenny, Alyna khan, Amit V. Khera, Yun Li Verified, Iman K. Martin, Josep M. Mercader, Maggie Ng, Laura M. Raffield, Alex P. Reiner, Robb Rowley, Daniel J. Schaid, Adrienne M. Stilp, Ken Wiley, Riley Wilson, John Witte, Pradeep Natarajan, Clement Adebamowo, Paul L. Auer, Jennifer E. Below, Palwende Romuald Boua, Kristin Boulier, Michael Bowers, Joseph Breeyear, Nilanjan Chatterjee, Tinashe Chikowore, Jaewon Choi, Nancy Cox, Sinead Cullina, Burcu F Darst, Aaron Deutsch, Yi Ding, Todd Edwards, Eleazar Eskin, Segun Fatumo, Jose C. Florez, José Miguel Florez, José Fernando Flórez, Nelson B. Freimer, Tian Ge, Daniel H Geschwind, Chris R. Gignoux, Mark O Goodarzi, Xiuqing Guo, Christopher A. Haiman, Neil A. Hanchard, Scott Hazelhurst, Susan R. Heckbert, Jibril B. Hirbo, Kangcheng Hou, Qinqin Huang, Alicia Huerta, Guoqian Jiang, Katherine Johnston, Linda Kachuri, Takashi Kadowaki, Abram Bunya Kamiza, Sarah L. Kerns, Joohyun Kim, Iain R. Konigsberg, Charles Kooperberg, Matt Kosel, Peter Kraft, Soo-Heon Kwak, Leslie Lange, Loic Le Marchand, Hyunsuk Lee, Aaron Leong, Meng Lin, Kirk E. Lohmueller, Ruth J. F. Loos, Kevin Lu, Alisa Manning, Alicia Martin, Hilary Abom Martin, Rasika A. Mathias, James B Meigs, Rachel Mester, Mariah C. Meyer, Tyne Miller-Fleming, Braxton D. Mitchell, Nicola Mulder, Jie Na, Kristjan Norland, Loes Olde Loohuis, Suna Onengut-Gumuscu, Roel A. Ophoff, Päivi Pajukanta, Bogdan Pasaniuc, Aniruddh Patel, Ulrike Peters, Jimmy Phuong, Michael Preuss, Bruce M. Psaty, Michèle Ramsay, Kenneth Rice, Stephen F. Rich, Jerome I. Rotter, Yunfeng Ruan, Lori C. Sakoda, Philip Schroeder, Jonathan A Shortt, Megan Shuey, Xueling Sim, Roelof A.J. Smit, Johanna Smith, Lucia Sobrin, Daniel O. Stram, Ken Suzuki, Lukasz Szczerbinski, Ran Tao, Bamidele Tayo, Timothy Thornton, Buu Truong, Miriam S. Udler, David van Heel, Luciana B. Vargas, Vidhya Venkateswaran, YING WANG, Jennifer A. Wessel, Laura Wiley, Lynne R Wilkens, Genevieve L Wojcik, Quenna Wong, Toshimasa Yamauchi, Lisa R. Yanek, Yue Stell Yu, Haoyu Zhang, Yuji Zhang, Michael Zhong, Nicholette Allred, Ethan Lange, Ravi Mandia, Ebuka Oneyobi, Bryce Rowan, Siram Sankararaman, Dan Schaid, Dan Schrider, Ruhoilah Shemirani, Lauren Stalbow, Teresa Tusie, David Conti
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The American Journal of Human Genetics
Verified
Opportunities, resources, and techniques for implementing genomics in clinical care
1. Manolio TA Chisholm RL Ozenberger B et al. Implementing genomic medicine in the clinic: the future is here. Genet Med. 2013; 15: 258-267 2. Khera AV Chaffin M Aragam KG et al. Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. Nat Genet. 2018; 50: 1219-1224 3. Orlando LA Wu RR Myers RA et al. Clinical utility of a Web-enabled risk-assessment and clinical decision support program. Genet Med. 2016; 18: 1020-1028 4.
Uncracking the code to a healthier you
DNA (or “deoxyribonucleic acid”) is the hereditary material in humans and almost all other organisms. It is the code of life. Everything that makes you who you are is determined in part by your DNA. Sometimes our DNA can protect us from disease while other times our unique codes can predispose us to it. We live in a time of significant advances in medicine, especially for cancer patients, who benefit from an accelerated pace of lifesaving discoveries.
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