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ArticleOnline now102884Open access Affiliations & Notes 1Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA 2Department of Radiation Oncology, University of Pittsburgh, Pittsburgh, PA, USA 3Molecular Imaging Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA 4Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA...
Keywords neuroblastoma glypican-2 GPC2 monoclonal antibody antibody humanization gamma/delta TCR antibody-TCR AbTCR chimeric antigen receptor CAR cell therapy CD30 Introduction Neuroblastoma is the second most frequently occurring extracranial solid tumor in children, accounting for 8%–10% of all pediatric cancers and 15% of cancer-related deaths in children.1 A major challenge in treating many cancers, including neuroblastoma, is the lack of effective therapeutic targets.
Since honey has a therapeutic role in the treatment of many diseases, we investigated the content of phenolic compounds and the antioxidant activity in acacia ( Robinia pseudoacacia L.), chestnut ( Castanea sativa Mill.) and lime-tree ( Tilia spp.) honey originating from Croatia and Germany. Total phenols, flavonols, and flavanols contents were observed at higher levels in Croatian Castanea honey compared to German Castanea honey.
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