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Articles by Ruiling Liu
Regulatory T cells in autoimmune diseases: biological mechanisms, clinical translation, and translational challenges
Abstract Autoimmune diseases (ADs) are a group of inflammatory disorders triggered by aberrant immune responses against autoantigens and the breakdown of immune tolerance. Current therapeutic strategies, such as glucocorticoids and immunosuppressants, exert largely non-specific immunomodulation and are frequently associated with substantial adverse effects upon long-term administration. As such, these approaches are often insufficient to re-establish immune homeostasis.
Diet-metabolism-transcription axis modulates the sensitivity to CDK4/6 inhibitors through RB1 in prostate cancer
Advances in Psoriasis Research: Decoding Immune Circuits and Developing Novel Therapies
This version is not peer-reviewed. Lanying Wang,Ruiling Liu,Yulu Tang,Yuanfang Ma,Enmei Wang,Qingguo Ruan *,Shijun J Zheng * Lanying Wang,Ruiling Liu,Yulu Tang,Yuanfang Ma,Enmei Wang,Qingguo Ruan *,Shijun J Zheng * You are already at the latest version Psoriasis is a chronic inflammatory autoimmune skin disease characterized by erythematous plaques covered with silvery-white scales, often accompanied by systemic complications such as psoriatic arthritis and cardiovascular diseases.
Characteristics of survivors enrolled in the World Trade Center Health Program
Abstract The World Trade Center (WTC) Health Program is a limited federal health care program that provides medical monitoring and treatment for WTC-related health conditions to responders and survivors impacted by the terrorist attacks on September 11, 2001.This study described the characteristics of the Program survivor members (who lived, worked, went to school, daycare or adult daycare or present in the New York City Disaster Area of 9/11/2001) to stimulate innovative ideas for improving...
The Invasion of Galinsoga quadriradiata into High Elevations Is Shaped by Variation in AMF Communities
3. Discussion As nonnative plant species move into new environments, the success and extent of their invasion can be limited by environmental conditions and biotic interactions. As far as we know, many current studies focus on the impact of abiotic factors on the dispersal of invasive plants along the altitude, while the impact of biotic factors, such as microorganisms, has not received enough attention.
Cuticular Wax Triterpenes Maintain Storage Quality of Blueberries by Reducing Water Loss
Open AccessArticle by 1, 2, 2, 2, 2, 2,* and 1,* 1 State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources/Guangdong, Provincial Key Laboratory of Postharvest Science of Fruits and Vegetables/Engineering Research Center of Southern Horticultural Products Preservation, Ministry of Education, College of Horticulture, South China Agricultural University, Guangzhou 510642, China 2 Key Laboratory of Post-Harvest Handing of Fruits, Ministry of Agriculture and Rural...
Safety Monitoring of mRNA Vaccines Administered During the Initial 6 Months of the U.S. COVID-19 Vaccination Program: Reports to Vaccine Adverse Events Reporting System (VAERS) and v-safe
Hannah G. Rosenblum, Julianne M. Gee, Ruiling Liu, Paige L. Marquez, Bicheng Zhang, Penelope Strid, Winston E. Abara, Michael M. McNeil, Tanya R. Myers, Anne M. Hause, John R. Su, Bethany Baer, David Menschik, Lauri E. Markowitz, Tom T. Shimabukuro, David K. Shay doi: https://doi.org/10.1101/2021.10.26.21265261 Abstract Background In December 2020, two mRNA-based COVID-19 vaccines were authorized for use in the United States.
Treating Autoimmune Diseases by Targeting IL-23 with Gene-Silencing Pyrrole-Imidazole Polyamide
Xiaozhen He, Ruiling Liu, Tingting Fan, Xiaowen Huang, Chunlei Wu, Wu Su, Ting Wang and Qingguo Ruan J Immunol April 15, 2020, 204 (8) 2053-2063; DOI: https://doi.org/10.4049/jimmunol.1901215 Key Points Polyamide targeting IL-23 specifically inhibits the expression of IL-23. Polyamide targeting IL-23 is effective in treating psoriasis and EAU in mice. Abstract Autoimmune diseases are a physiological state that immune responses are directed against and damage the body’s own tissues.
Treating Autoimmune Diseases by Targeting IL-23 with Gene-Silencing Pyrrole-Imidazole Polyamide
Xiaozhen He, Ruiling Liu, Tingting Fan, Xiaowen Huang, Chunlei Wu, Wu Su, Ting Wang and Qingguo Ruan J Immunol March 13, 2020, ji1901215; DOI: https://doi.org/10.4049/jimmunol.1901215 Key Points Polyamide targeting IL-23 specifically inhibits the expression of IL-23. Polyamide targeting IL-23 is effective in treating psoriasis and EAU in mice. Abstract Autoimmune diseases are a physiological state that immune responses are directed against and damage the body’s own tissues.
miR-340 Alleviates Psoriasis in Mice through Direct Targeting of IL-17A
miR-340 Alleviates Psoriasis in Mice through Direct Targeting of IL-17A Jiang Bian, Ruiling Liu, Tingting Fan, Lijuan Liao, Shaowen Wang, Wenwen Geng, Ting Wang, Weiyun Shi and Qingguo Ruan J Immunol September 1, 2018, 201 (5) 1412-1420; DOI: https://doi.org/10.4049/jimmunol.1800189
miR-340 Alleviates Psoriasis in Mice through Direct Targeting of IL-17A
miR-340 Alleviates Psoriasis in Mice through Direct Targeting of IL-17A Jiang Bian, Ruiling Liu, Tingting Fan, Lijuan Liao, Shaowen Wang, Wenwen Geng, Ting Wang, Weiyun Shi and Qingguo Ruan J Immunol July 16, 2018, ji1800189; DOI: https://doi.org/10.4049/jimmunol.1800189
Acute Illnesses and Injuries Related to Total Release Foggers - 10 States, 2007-2015
A previous study identified 466 acute TRF-related illnesses in eight states during 2001–2006 (1) for a crude average annual incidence rate of seven cases per 10 million population. This study identified 3,222 cases in 10 states during 2007–2015, with an average annual incidence rate of 27 per 10 million population. This increase likely resulted from including all PCC cases from Florida, Texas, and Washington and conducting a more comprehensive search for TRF-related cases in the SENSOR database.
Negative Immune Regulator TIPE2 Promotes M2 Macrophage Differentiation through the Activation of PI3K-AKT Signaling Pathway
Macrophages play important roles in the regulation of the innate and adaptive immune responses. Classically activated macrophages and alternatively activated macrophages are the two major forms of macrophages and have opposing functionalities. Tumor necrosis factor-?-induced protein 8–2 is expressed primarily by immune cells and negatively regulates type 1 innate and adaptive immune responses to maintain immune tolerance.
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