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Runying Y. Yang

As seen in: Nature, Cell Reports
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Articles

Targeting p130Cas- and microtubule-dependent MYC regulation sensitizes pancreatic cancer to ERK MAPK inhibition

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By Andrew Waters, Bjoern Papke, Craig Goodwin, G. Aaron Hobbs, J. Nathaniel Diehl, Runying Y. Yang, Katherine Walsh, Rita Sulahian, James M McFarland, Kevin S. Kapner, Thomas Gilbert, Clint A. Stalnecker, Sehrish Javaid, Anna Barkovskaya, Kajal R Grover, Devon R. Blake, Antje Schaefer, Katherine Nowak, Jennifer E. Klomp, Tikvah K Hayes, Nanyun Tang, Kaisheng Chen, Yingyao Zhou, Manpreet Kalkat, Laura Herring, Lee Graves, Linda Z. Penn, Hongwei Yin, Andrew J. Aguirre, William Hahn, adrienne cox, Channing J. Der, A. Cole Edwards, Priya S. Hibshman, Michelle Kassner, Olga Tanaseichuk
| Cell Reports Verified
Main text (Cell Reports 35, 109291; June 29, 2021) There are errors in two figures of this paper. In Figure 6C, the p130Cas, total ERK, and phospho-p130Cas immunoblots inadvertently display alternative exposures from Figure 3D. In Figure S10B, images of four KX2-391-treated ex vivo tumors were inadvertently duplicated in the ERKi-treated ex vivo tumors.
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Slc7a5 regulates Kv1.2 channels and modifies functional outcomes of epilepsy-linked channel mutations

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By Victoria Baronas, Luis Morales, Runying Y. Yang, Simonetta Sipione
| Nature Verified
We have previously reported marked variability of Kv1.2 gating parameters in commonly used expression systems, suggesting these channels are subject to unrecognized regulatory mechanisms18,24. To identify interacting proteins, we used 1D4 affinity purification of cross-linked channel complexes, followed by quantitative LC–MS/MS mass spectrometry.
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