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sadaf Valeh Sheida

As seen in: Cell Reports, medRxiv
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Articles

Ski2-like helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses

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By Nicole L. Batenburg, Aruna Arumugam, John Walker, sadaf Valeh Sheida, Anja-Katrin Bielinsky, Markus C. Wahl, Jean-Yves Masson, Xu-Dong Zhu, Shixin Cui
| Cell Reports Verified
Keywords ASCC2 ASCC3 replication stress PCNA ubiquitylation fork reversal ATR activation RAD51-dependent recombination genomic stability Research topic(s) CP: genomics Introduction Replication stress represents a major source of genomic instability that can drive tumorigenesis.1,2,3 Human cells have evolved several interconnected responses to replication stress.4,5,6 Upon fork stalling, the uncoupling of leading and lagging strand DNA synthesis generates single-stranded DNA (ssDNA).
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The expression alteration of Golim4 (Gpp130) and its prognostic value in epithelial ovarian cancer

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By Akram Gholipour, Seyed Javad Mowla, sadaf Valeh Sheida, Hossein Bayat Varchaghi
| medRxiv
The authors have declared no competing interest. This study did not receive any funding I confirm all relevant ethical guidelines have been followed, and any necessary IRB and/or ethics committee approvals have been obtained.
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