Samantha Wolfe

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Introduction The incidence of differentiated thyroid cancer is rising; it is now the 7th most common cancer worldwide, with >800,000 new cases annually (1). Most cases are low risk with excellent outcomes. In the U.S., all-cause mortality for low-risk disease is <1% (2) and recurrence is <5% (3). Given the expectation of long-term survival, attention has shifted to avoiding overtreatment and using healthcare resources judiciously.