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Samuel Bosomprah on Muck Rack

Samuel Bosomprah

As seen in: Nature, Epidemiology and Infection, PLOS, PLOS ONE, Frontiers in Immunology, MDPI, medRxiv
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Articles

Multi-site wastewater metagenomics reveals geographically distinct microbial communities and plasmid-mediated antimicrobial resistance co-selection in Zambia

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By Charlie C. Luchen, Marlon Banda, Jay Sikalima, Innocent Mwape, Kennedy Chibesa, Noah Hull, Chipo Mambo, Mwelwa Chibuye, Precious Simushi, Suwilanji Silwamba, Michael Njuguna, Fatim Jallow, Dhally M. Menda, Victor Daka, Caroline C. Chisenga, Michelo Simuyandi, Samuel Bosomprah, Doreen M. Shempela, Walter Muleya, Paul Simusika, Karen Sichinga, Edgar Simulundu, Roma Chilengi, Dickson Sandala, Mapeesho Kamayani, Mike Masona, Ben Katowa, Keith Kabengele, Lugard Sichalwe, Clement Phiri, Ephraim Chandela, Chilufya Mulenga, Michael Kachumi
| Nature Verified
Abstract Antimicrobial resistance (AMR) poses a disproportionate burden in low- and middle-income countries, yet comprehensive environmental surveillance, particularly for plasmid-mediated resistance, remains critically limited in sub-Saharan Africa. Wastewater systems harbour diverse microbial communities with a high potential to mobilise antibiotic resistance genes (ARGs), thereby driving the environmental dissemination of resistance.
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Pre-vaccination biomarkers of enteric dysfunction, inflammation and nutritional status associate with seroconversion to oral cholera vaccine and are perturbed during natural infection

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By Fraser Liswaniso, Bernard J Phiri, Mwelwa Chibuye, Charlie C. Luchen, Kennedy Chibesa, Mutinta Muchimba, Roma Chilengi, Samuel Bosomprah, Caroline C. Chisenga, Dennis Ngosa
| Frontiers in Immunology
Abstract Background: Oral cholera vaccines (OCVs) show variable immunogenicity in endemic settings. Host factors including enteric dysfunction, systemic inflammation, and nutritional status may influence responses, yet their role in shaping OCV immune responses is not fully understood.
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Metabolic syndrome and its risk factors among adults living with HIV receiving antiretroviral therapy in Zambia: an ambidirectional cohort study

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By Benson M. Hamooya, Samuel Bosomprah, Sepiso K. Masenga, Katongo H. Mutengo, Lukundo Siame, Precious Simushi, Tuku Mwakyoma, Wilbroad Mutale, Hikabasa Halwiindi, Roger Bedimo, Sadeep Shrestha, Chitalu Chanda, Douglas Heimburger, Loren Lipworth, Chilala Cheelo, Jolezya Mudenda
| Nature Verified
Abstract Effective antiretroviral therapy (ART) has significantly improved the survival of people living with HIV (PWH) while concurrently ushering in a new challenge of cardiometabolic complications. Despite advancements in treatment, there is a paucity of epidemiological and longitudinal data on metabolic changes among PWH receiving ART in sub-Saharan Africa, particularly with the adoption of integrase strand transfer inhibitors (INSTIs).
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