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Sanjana Prakash on Muck Rack

Sanjana Prakash

Atlanta, Southern Asia
As seen in: Nature, MDPI, NDTV, Taylor & Francis Online, Tom's Guide, NewsBreak, TWICE, Gadgets 360, Inferse
Tech Journalist. Former News Editor at @tomsguide | Former Anchor-Producer @NDTV | Tech | Travel | Tennis | Books | Start ups | Cardiff University Alumni
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Articles

Neuronal lipid droplets play a conserved and sex-biased role in maintaining whole-body energy homeostasis

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By Romane Manceau, Celena M Cherian, Danie Majeur, Colin Miller, Frederick Boisjoly, Lianna W. Wat, Charlotte F Chao, Audrey Labarre, Sanjana Prakash, Sebastien Audet, Lewis R Depaauw-Holt, Benjamin Rogers, Anthony Bosson, Puja Biswas, Joyce Xi, Niyoosha Yoosefi, Yi Xia, Alisa Hui, Jared Vander Zwaag, Khalil Bouyakdan, Pavel Kotchetkov, Caroline Daneault, Martine Tétreault, Marie-Eve Tremblay, Matthieu Ruiz, Baptiste Lacoste, J. Parker, Ciaran Murphy-Royal, Tao Huan, Stephanie Fulton, Elizabeth Rideout, Thierry Alquier, Jasper D. Fisher, J. Beatrice Liston, Jennifer A. Bako, Serena Hollman, Catrina A. S. Callow, Neele Schikora, Niki Shahraki, Demetra Rodaros, Ghazal Fallahpour
| Nature Verified
Abstract Lipids are essential for neuron development and physiology1,2,3. Yet, the central hubs that coordinate lipid supply and demand in neurons remain unclear4. Here we show the presence and functional significance of neuronal lipid droplets (nLDs) in vivo using invertebrate and vertebrate models. We validate5 the presence of nLDs in vivo and demonstrate that triglyceride metabolism enzymes and LD-associated proteins control nLD formation through both canonical and recently discovered pathways6.
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Formulation and optimization of cilnidipine solid dispersion-based sublingual films using D-optimal mixture design

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By H. N. Shivakumar, Megha Kamath, Avichal Kumar, Sanjana Prakash
| Taylor & Francis Online
Abstract Cilnidipine (CIL) is a calcium channel blocker that exhibits low oral bioavailability (∼13%) due to poor aqueous solubility and extensive first-pass metabolism. This study aimed to develop rapidly disintegrating sublingual films of CIL solid dispersions (CILSD) to overcome these limitations. Phase solubility studies identified polyethylene glycol 6000 as the most suitable carrier, as it significantly improved (p < 0.001) the drug solubility.
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Formulation and Evaluation of Polymeric Spherical Agglomerates-Based Porous Orodispersible Tablets of Cilnidipine

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By Yahya Alhamhoom, Sanjana Prakash, Avichal Kumar, Shivakumar Hagalavadi Nanjappa
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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