Scellig SD. Stone

Abstract Electrical brain stimulation has been used to treat epilepsy with therapeutic success, but without complete understanding of its cellular mechanisms of seizure suppression. Using acute human brain slices obtained from pharmaco-resistant epilepsy patients, we delivered high-frequency, high-intensity extracellular electrical stimulation while recording from neocortical layer 2/3 pyramidal neurons (PNs), fast-spiking interneurons (FSINs), and non-fast-spiking interneurons (nFSINs).

Abstract Neuronal-glioma interactions are increasingly recognized as critical in the development and progression of central nervous system tumors. Recent research highlights that gliomas can integrate into neural circuits through various mechanisms, including the synaptogenic factor thrombospondin-1 (TSP-1). This new mechanistic understanding of cancer neuroscience allows for novel insights into target discovery.

Keywords vision minimally recognizable configurations electrocorticography stereo EEG human neurophysiology object perception top-down signals computational models of vision Research topic(s) CP: Neuroscience Introduction Visual object recognition is robust to an extensive range of image transformations that produce different retinal projections of the same stimulus.1,2 For example, we can easily recognize an object when presented in a wide range of positions, scales, or viewpoints.3,4 A...