Mikias Negussie on Muck Rack

Mikias Negussie

As seen in: Nature, Flipboard, The Journal of Biological Chemistry
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Articles

Predicting therapeutic clinical trial enrollment for adult patients with low- and high-grade glioma using supervised machine learning

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By Mulki Mehari, Gayathri Warrier, Abraham Dada, Aymen Kabir, Aden P. Haskell-Mendoza, Arushi Tripathy, Rohan jha, Edwin Nieblas-Bedolla, Joshua Jackson, Ariel Gonzalez Verified, Tara Dalton, Mikias Negussie, César Gonzales, Vardhaan S. Ambati, Annick Desjardins, Saritha Krishna, Susan Arterian Chang, Alyx B. Porter, Peter E. Fecci, Todd C Hollon, Ugonma N. Chukwueke, Kimberly Badal, Annette M. Molinaro, Shawn Hervey-Jumper, Ellery H. Reason, Ann Marie Flusche, Sheantel Reihl
| Flipboard
9 hours ago Despite what tech CEOs might say, large language models are not smart in any recognizably human sense of the word. On June 13, 1863, a curious letter to the editor appeared in The Press, a then-fledgling New Zealand newspaper. Signed “Cellarius,” it warned of an encroaching “mechanical kingdom” that …
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Gabapentinoids confer survival benefit in human glioblastoma - Nature Communications

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By Joshua D. Bernstock, Vardhaan S. Ambati, Benjamin R. Johnston, Mikias Negussie, Abraham Dada, Lennard Spanehl, Youssef E. Sibih, Rania A Mekary, Saef Izzy, Scellig SD. Stone, Yi Lu, Minesh P. Mehta, Yazmin Odia, Gregory K. Friedman, E. A. Chiocca
| Nature Verified
Abstract Neuronal-glioma interactions are increasingly recognized as critical in the development and progression of central nervous system tumors. Recent research highlights that gliomas can integrate into neural circuits through various mechanisms, including the synaptogenic factor thrombospondin-1 (TSP-1). This new mechanistic understanding of cancer neuroscience allows for novel insights into target discovery.
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Multivalent lipid targeting by the calcium-independent C2A domain of synaptotagmin-like protein 4/ granuphilin

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By Aml A Alnaas, Abena Watson-Siriboe, Sherleen Tran, Mikias Negussie
| The Journal of Biological Chemistry Verified
Author contributions: A.A.A., A.W.-S., N.L.C., C.T.S., H.L., and J.D.K. conceptualization; A.A.A., A.W.-S., S.T., M.N., J.A.H., J.R.O., N.L.C., C.M., and J.D.K. data curation; A.A.A., A.W.-S., S.T., M.N., J.A.H., J.R.O., N.L.C., C.M., R.R., H.L., and J.D.K. formal analysis; A.A.A., A.W.-S., S.T., M.N., J.A.H., J.R.O., N.L.C., B.M.H., J.O., T.L., C.M., and J.D.K. investigation; A.A.A., S.T., M.N., B.M.H., C.M., and J.D.K. writing-original draft; A.A.A., S.T., M.N., J.A.H., N.L.C., B.M.H.,...
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