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Scott Matson

As seen in: Substack, Thorax, Kansas City Star, The Lancet, medRxiv, Dialnet - Universidad de La Rioja, European Respiratory Journal, Chest, ersnet.org, RheumNow and

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Articles

Episode 1: Adam Cifu

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By Scott Matson
| Substack
Current time: 0:00 / Total time: -1:10:20 Audio playback is not supported on your browser. Please upgrade. What does it actually mean to practice evidence-based medicine? In this episode, we sit down with Adam Cifu to unpack the gap between clinical evidence and real-world decision making. We explore how data is interpreted at the bedside, why guidelines don’t always translate cleanly into practice, and what it takes to think clearly in the face of uncertainty.
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Incentives and Noninferiority Designs

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By Scott Matson
| Sensible Medicine Newsletter
Noninferiority trials can play an important role in advancing medical care. JAMA published a terrific Users’ Guide on how to read these years ago. There are times, however, when researchers employ a non-inferiority design where a superiority design would seem to make more sense. There are also frequent debates about non-inferiority margins and the endpoints used in these trials. Today, Dr. Scott Matson considers the incentives that drive these decisions.
Open in Who Shared Issue with article?

Incentives and Noninferiority Designs

|
By Scott Matson
| Substack
Noninferiority trials can play an important role in advancing medical care. JAMA published a terrific Users’ Guide on how to read these years ago. There are times, however, when researchers employ a non-inferiority design where a superiority design would seem to make more sense. There are also frequent debates about non-inferiority margins and the endpoints used in these trials. Today, Dr. Scott Matson considers the incentives that drive these decisions.
Open in Who Shared Issue with article?
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