Seth Lederman
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Articles by Seth Lederman
Franchise Ownership Psychology: Why Some Thrive While Others Burn Out
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of “Profits are Better Than Wages.” Franchising is often seen as the safer path to entrepreneurship. It provides a proven system for operations, brand recognition and built-in and ongoing support. Although statistics can give a simple road map as to why some franchise owners thrive while others barely survive, it isn’t just about things such as capital, location or timing.
Corporate Job Versus Franchise Ownership: Which Path Builds More Freedom?
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." At some point in any mid-career professional’s lifetime, it is natural to ask the question about what the future holds and if there is a quicker way to gain freedom over one's work-life balance. Corporate jobs offer things like a steady paycheck, regular promotions, performance reviews and meetings about having meetings. If those are things that you enjoy, stay put.
Which Personality Types Are Best For Franchise Ownership Success?
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." Not everyone is wired for franchise ownership. Although people often speak of success in terms of financial standing, which includes factors such as investment ranges, royalty structures and revenue models, one of the most overlooked factors in long-term success has nothing to do with capital.
Americans Deserve Better Lyme Disease Prevention
RCP Last December, HHS Secretary Robert F. Kennedy Jr. convened patients, clinicians, and researchers for a historic Lyme disease roundtable. He spoke personally about spending time in nature and picking ticks off himself. The Secretary lamented that the risk of Lyme disease has made the woods “hazardous across this country,” making it harder for American children to enjoy the outdoors as part of a healthier lifestyle. It was a powerful, overdue moment of recognition.
Forbes JAPAN 公式サイト（フォーブス ジャパン）
セス・レダーマンは、FrannexusのCEOであり、受賞歴を持つフランチャイズ・コンサルタント。著書に『Profits are Better Than Wages』がある。 フランチャイズの増加が過去最高に達する一方で、フランチャイズという概念自体は19世紀半ばに始まっている。アイザック・シンガーのミシンが全米を席巻した時代だ。そこからフランチャイズは発展を遂げ、1890年にはコカ・コーラが採用する実用的な選択肢となった。さらに第二次世界大戦後、ファストフード産業とともに新たな形をとるようになった。 フランチャイズは、あらゆる背景をもつ起業家を惹きつけてきた。かつて旅人が土地ごとの料理を味わったように、移動は「その土地ならでは」の体験だった。しかし今では、世界のほとんどあらゆる場所に見覚えのある店構えがあるため、どの都市にもある程度は「自分の場所」のような感覚が生まれる。...
Rewriting The American Opioid Story: How The Healthcare Industry Can Help
Seth Lederman, M.D., is co-founder, CEO and chairman of Tonix Pharmaceuticals, a biotech company dedicated to developing novel medicines. For decades, American culture has portrayed the illegal drug trade as a permanent fixture, both inevitable and profitable. From film classics The French Connection and The Godfather to series like Breaking Bad and Dopesick, popular storylines normalize illicit narcotics as a constant backdrop.
Franchise Myth-Busting: What Prospective Owners Need To Know
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." Although the rise in franchising has hit an all-time high, franchising as a concept began in the mid-1800s, when Isaac Singer’s sewing machine swept the country. From there, franchising evolved into a viable option used by Coca-Cola in 1890; and after World War II, it took new shape with the fast food industry. Franchising has attracted entrepreneurs from all walks of life.
Forbes JAPAN 公式サイト（フォーブス ジャパン）
Seth Lederman氏、受賞歴のあるフランチャイズコンサルタントで著書「Profits are Better Than Wages（利益は賃金より優れている）」の著者であり、FrannexusのCEO。 国際フランチャイズ協会の推計によると、フランチャイズ業界は2025年に2万以上の新規フランチャイズ店舗を追加すると予想されている。これは前年比で世界のフランチャイズ事業所数が少なくとも2.5%増加することを意味する。フランチャイズ事業所の増加に伴い、必然的に雇用も生まれる。2024年にはフランチャイズ業界で880万人が雇用され、2025年にはその数が約900万人に増加すると予想されている。フランチャイズは実証済みのビジネスモデルにより比較的リスクの低い選択肢とされているが、すべてが持続可能というわけではない。特にトレンドやブームに依存するものはなおさらだ。一般的な投資家にとって、安定した伝統的なフランチャイズを選ぶべきか、それとも市場で爆発的に成長するフランチャイズを選ぶべきなのだろうか？ トレンド型と伝統型フランチャイズ：メリットとデメリット...
A Good Idea That Broke Bad: Why Pain Is Still a Vital Sign – DC Journal - InsideSources
When U.S. medicine declared pain “the fifth vital sign” in the 1990s, it was a call to take patients seriously. At its core was the belief that tracking pain as carefully as the other four vital signs—heart rate, blood pressure, temperature, and breathing rate—would improve care. But when opioid promoters co-opted this new standard with unethical marketing campaigns, prescriptions for opioid painkillers surged throughout the 2000s.
Trendy Versus Classic Franchises: Which Is Best To Invest In?
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." According to the International Franchise Association estimates, the franchise industry was expected to add more than 20,000 new franchise units in 2025. That is an increase of at least 2.5% in franchise establishments globally from the previous year.
How Franchise Fees Work-And What You’re Really Paying For
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." getty For many entrepreneurs, buying a franchise is the best way to move into business ownership. Franchises come with a proven business model, built-in brand recognition and ongoing support. But that does not equal guaranteed success.
Forbes JAPAN 公式サイト（フォーブス ジャパン）
セス・レダーマン氏は、FrannexusのCEOであり、受賞歴のあるフランチャイズコンサルタント、著書「Profits are Better Than Wages（利益は賃金より良い）」の著者である。 フランチャイズの購入は新規事業の立ち上げよりも有利な点があるが、成功を保証するものではない。新しいことに挑戦する際には、必ず課題が伴う。フランチャイズの成否を決める要因は多岐にわたり、対人関係に関するものもあれば、そうでないものもある。私がよく目にするのは、フランチャイズ経営の実現可能性を制限する共通のミスだ。フランチャイズを始めようと決めているなら、収益性の高い事業のために避けるべきことは以下の通りだ。 1.
10 Of The Most Common Mistakes New Franchise Owners Make
Seth Lederman, CEO of , award-winning franchise consultant and author of "Profits are Better Than Wages." Buying a franchise comes with advantages over new business startups, but it is not a guarantee for success. Whenever you switch gears to try something new, challenges are attached. Many factors determine how well a franchise does, some interpersonal, others not, and there are common mistakes I see that can limit the viability of franchise ownership.
A CXCR4 partial agonist improves immunotherapy by targeting immunosuppressive neutrophils and cancer-driven granulopoiesis
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Keywords immunosuppressive neutrophil MDSC polymorphonuclear myeloid-derived suppressor cells gastric cancer TFF2 CXCR4 granulopoiesis partial agonist Get full text access Log in, subscribe or purchase for full access. References 1. Veglia, F. ∙ Sanseviero, E. ∙ Gabrilovich, D.I. Myeloid-derived suppressor cells in the era of increasing myeloid cell diversity Nat. Rev. Immunol. 2021; 21:485-498 2. van Vlerken-Ysla, L. ∙ Tyurina, Y.Y. ∙ Kagan, V.E. ...
By Jin Qian, Chenkai Ma, Quin T Waterbury, Xiaofei Zhi, Christine Moon, Ruhong Tu, Hiroki Kobayashi, Feijing Wu, Biyun Zheng, Yi Zeng, Hualong Zheng, Yosuke Ochiai, Ruth White, Ryan H. Moy, Arnold Han, Seth Lederman Verified, Timothy C. Wang, David W. Harle, Jonathan S. LaBella, Leah B. Zamechek, Bruce L. Daugherty
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Cell Press
Verified
Seven Interpersonal Factors To Consider When Choosing A Franchise
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." getty Investing in a franchise is not just a heavy financial decision; it is a long-term commitment. It takes capital to invest in a franchise model, but you also have to understand how interpersonal interactions will affect your work-life balance and personal satisfaction.
Franchise Opportunities For Entrepreneurs To Focus On
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." Franchising can be an attractive business model for entrepreneurs looking to invest in a proven system while minimizing some of the risks associated with a typical business startup. Today, I find that certain industries stand out as prime opportunities to grow wealth due to market trends, consumer demand and economic resiliency.
Council Post: How To Solve Electric Vehicle Hurdles Through Innovation
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." Recent forecasts predict that by 2030, as many as 35% of all automobile sales in the U.S. will be electric vehicles (EV). According to the U.S. Department of Energy, that means nearly will switch from gas-powered vehicles to electric-run ones.
Franchise Journal Magazine | News | Emerging Franchise Businesses
By Seth Lederman • January 1, 2025 In the world of franchising, established names often dominate headlines, but emerging franchises are carving out their own niche, offering innovative concepts and fresh opportunities for entrepreneurs. From tech-driven ventures to sustainable lifestyle brands, these rising stars are reshaping the franchising landscape. For those looking to invest in the future of business, understanding these trends and evaluating these burgeoning franchises is key.
Council Post: Franchise Or Chain Establishment: Which One Makes More 'Cents' For You?
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." Often I've found that people who are looking for business opportunities are unclear about what the differences are between a franchise and a chain establishment. Those looking to invest should also understand what makes them different so they can choose the best investment for success.
Why Franchises are a Great Fit for U.S. Military Veterans
U.S. military veterans bring a unique set of skills and experiences to the civilian workforce, making them valuable assets in various industries. Franchising offers a structured, supportive business model that aligns closely with the qualities and training veterans receive during their military service. The discipline, leadership, and teamwork that are hallmarks of military life translate well into running a franchise. 1.
Franchises Empowering Veterans: A Path to Entrepreneurship
For many veterans, the transition from military service to civilian life can be a daunting one. Finding a new career that allows them to use their skills and leadership can be challenging. That’s why more veterans are turning to franchise ownership as a way to start their own business while benefiting from a proven system. One franchise paving the way is FastSigns, which offers a 50% reduction in franchise fees for veterans and first responders, giving them a clear path to becoming their own boss.
Next Day Access Franchise Offers a Path to Success
As we honor the brave men and women who have served our country, we also celebrate the immense value they bring to the business world, especially as franchise owners. Next Day Access, a leader in accessibility and mobility solutions, is committed to supporting veterans by offering them a discount on franchise ownership. This not only shows appreciation for their service but also creates opportunities for veterans to excel in business.
A Lifeline for Veterans and a Cause for Businesses to Support
Veterans returning to civilian life often face challenges that are hard to imagine—ranging from post-traumatic stress disorder (PTSD) and traumatic brain injuries (TBI) to the isolation that can follow years of military service.
A Franchise on the Cutting Edge
Shattered Glass Art Studio SRQ has taken DIY to the next level of art creation. This isn't your average art class. Here, cut and tumbled glass lend its brilliant colors and transformative powers to its clients. They create custom art masterpieces every time, and have an experience that they want to share with family and friends. Husband and wife team Kevin and Nicole Berry opened their first Shattered Glass Art Studio in 2021.
Why Franchising is a Great Fit for Military Veterans
Franchising has become an attractive option for many individuals seeking to become entrepreneurs, and it holds particular appeal for military veterans. Veterans possess a unique set of skills, including discipline, leadership, and an unwavering commitment to following established systems—qualities that make them well-suited for success in the franchising world.
Veterans Already Have the Skills to be Successful Franchisers
As the son of a veteran who served a full 30-year career in the military (Marine Corp & Army), I grew up with a profound respect for those who serve and have served our country. Veterans come from all walks of life, bringing with them a diverse set of skills honed through years of dedication and sacrifice. These very skills, developed throughout their military service, are often what make veterans uniquely equipped to succeed in franchise business ownership.
Bet on a Vet 100: Empowering Veterans to Own a Franchise
The FCC Veterans Franchise Council has launched a $1,000,000 financial initiative to support veterans aspiring to own their own business. As part of this initiative, the first 100 veterans who qualify can receive up to $10,000 to help make their entrepreneurial dreams a reality.
Franchising: A Veteran-Friendly Business Opportunity
By Rudy Frederico • 01 Nov, 2024 Franchising has become an attractive option for many individuals seeking to become entrepreneurs, and it holds particular appeal for military veterans. Veterans possess a unique set of skills, including discipline, leadership, and an unwavering commitment to following established systems—qualities that make them well-suited for success in the franchising world.
Finding Fulfillment in Franchise Ownership: A New Chapter for Military Veterans
Transitioning from military service to civilian life can be both exciting and challenging for veterans. Many seek career paths offering structure, independence, and purpose while utilizing leadership and organizational skills honed in the military. For a growing number of veterans, franchise ownership offers an ideal solution, combining business ownership with a proven framework.
FASTSIGNS®’s Commitment to Veteran Franchisees
The franchising industry boasts a remarkable presence of veteran entrepreneurs, with former service members owning an impressive 1 in 7 franchises in the US. This represents a disproportionate yet welcome contribution, considering veterans comprise only 7% of the civilian adult population.
How Military Skills Lead to Franchise Success
Military veterans have made a significant mark in the world of business franchise ownership, capitalizing on the unique skills, experiences, and discipline they cultivated during their time in service. Veterans are well-suited to thrive in franchising, as the structure, systems, and support provided by franchises align with the operational frameworks they mastered in the military.
Why Veterans Thrive as Balloon Kings Franchise Owners
For military veterans, the transition from service to civilian life presents new challenges and opportunities. Many veterans look for careers where they can apply their leadership, discipline, and strategic thinking skills, and franchising offers a structured path to achieve success. A standout franchise for veterans is Balloon Kings®, founded in 2011 by Marine Corps combat veteran Gene Nifenecker II.
Council Post: Eight Important Skills For Franchise Ownership Success
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." Owning a franchise is similar to starting up your own business, the difference being that you are buying into a proven business model for success. Just because the business model is proven, however, doesn’t mean every franchise ownership is a guarantee of financial freedom and success. As with all business ownership, franchise owners must invest money, time and dedication.
Council Post: Tips For Breaking Into Franchising With Limited Funding
Seth Lederman, CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages.” Making money, especially in the current economy, can be a catch-22. You need capital to invest, but you need to invest to make more capital. Being stuck in a job or career you aren’t thriving, passionate about or downright don’t enjoy can be stifling.
Council Post: With The Economy Uncertain, Is Now The Time To Buy A Franchise?
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." The uncertainty and trepidation of what will happen in the economy and on the political stage are thick. A lot of people are starting to feel the pinch of the soaring cost of living, rising gas prices and interest rates being higher than before. Many workers are having a hard time paying their bills and are looking for an answer.
Council Post: The Five S’s To Consider When Choosing Franchise Ownership
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." As we roll into the second quarter of 2024, many resolve to enjoy more work/life satisfaction, increase their earning potential or just make an overall career change. Economic conditions , making it more critical than ever for those setting out on a new financial venture to be vigilant about their choices.
Council Post: Five Factors To Consider When Choosing Your Franchise Location
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." With the new year comes a promise of new opportunities. The economy continues to be uncertain, making many consider staying with the same old, same old, but what with the changing atmosphere of the workforce and individual ideation spurred by Covid-19, now might be the best time to think about taking on a new venture.
Council Post: Is 2024 The Year For You To Go It Alone With Franchise Ownership?
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." As we move into 2024, the political atmosphere is charged, and the economy…not so much. With so much uncertainty, many people wonder whether making a significant change to their current career path and livelihood is a good idea or a horrible mistake. A new business startup comes with a lot of risks, but the rewards are pretty amazing.
4 Tips For Navigating the World of Franchising
Franchising, a time-tested model for business growth and economic resilience, has long appealed to entrepreneurs and investors alike. Even amidst the ongoing twists and turns of economic trends, it has largely remained a steady fixture in the commercial landscape. Franchising is even more alluring when individuals lose their jobs and look for other, secure alternatives.
Council Post: Three Lessons For Anyone Looking To Become A Franchise Owner
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." Owning a franchise can be rewarding, exciting and lucrative, but it’s not right for everyone. You do need to choose the right franchise and understand everything that you are getting into to reap the full advantages of ownership. Even with a proven business model and plan, there will likely be challenges along the way.
Council Post: Five Critical Questions To Ask Yourself Before Becoming A Business Owner
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." As we close out the second half of 2023, economic times are uncertain at best. With high interest rates and costs of living, it is becoming increasingly difficult to get ahead, much less accumulate wealth.
Council Post: Six Interpersonal Traits To Consider Before Becoming A Business Owner
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." As we move into the second half of the year, many are finding that a dollar isn’t stretching as far as it did a year ago. One of the best ways to start securing a financial future and accumulating wealth that goes directly into your pocket is to become a business owner. Business ownership comes with advantages like freedom, control over your earnings and the ability to make your own decisions.
Council Post: Five Signs You Have Achieved Work-Life Balance
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." Now that we are almost three years out from the start of the pandemic and seemingly back to "business as usual," not everyone is feeling like they want the "usual." If you are tired of living the daily grind, you might be considering a change of pace. Work-life balance has become the new goal for many in the workforce.
Council Post: How To Start A Franchise On Low Capital
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." As we head fast through 2023, many are finding that the status quo isn’t cutting it anymore. Pre-pandemic, many settled for paying their dues, earning a paycheck and muddling along, but Covid-19 taught us that life is too short to be miserable and that there are alternatives to the daily grind. But what do you do if you want to create a startup but lack available capital?
Efficacy and Safety of Sublingual Cyclobenzaprine for the Treatment of Fibromyalgia: Results From a Randomized, Double‐Blind, Placebo‐Controlled Trial
Fibromyalgia (FM) affects an estimated 2–6% of people in the US, with symptoms including chronic multisite pain and disturbed sleep. TNX-102 SL is a novel, low-dose, sublingual formulation of cyclobenzaprine designed to be taken at bedtime. In this phase III, double-blind, multicenter, placebo-controlled trial, treatment with TNX-102 SL was associated with significant reductions in daily pain relative to placebo and was well tolerated by patients with FM.
Council Post: Four Factors To Consider Before Opening A Franchise
Share to Facebook Share to Twitter Share to Linkedin CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." getty Owning a business can be risky, so you need to put a lot of thought behind the type of business you choose to operate and the decisions you make along the way. Branding, structure and overall business strategies, for example, must be researched and contemplated.
Council Post: Weighing The Benefits And Challenges Of Franchise Ownership
CEO of Frannexus, award-winning franchise consultant and author of "Profits are Better Than Wages." getty Recently, the International Franchise Association released its outlook report for the future of franchising—and things are looking up! According to the study, job growth is steady and will likely continue as we find our new normal following the pandemic.
Efficacy and Safety of Sublingual Cyclobenzaprine for the Treatment of Fibromyalgia: Results From a Randomized, Double‐Blind, Placebo‐Controlled Trial
Abstract Objective To evaluate the efficacy and safety of TNX-102 SL, a once-nightly sublingual formulation of cyclobenzaprine, in reducing pain in patients with fibromyalgia (FM). Methods RELIEF was a double-blind, randomized, placebo-controlled trial. Overall, 503 patients received TNX-102 SL 2.8 mg for 2 weeks, followed by 5.6 mg for 12 weeks (248 patients), or matching placebo (255 patients). The primary end point was change from baseline at week 14 in the weekly average of daily pain scores.
Using Lessons From COVID-19 to Defend the World Against Emerging Threats
New COVID-19 boosters are rolling out, but the US still leads the world in daily pandemic deaths. At the same time, we’re one of over 80 countries (1) struggling to control monkeypox in regions where it is not endemic. Even polio is waging a comeback. Though these diseases are very different, this confluence of viruses and public health emergencies is unlike anything I’ve seen in my career, which started with the fight against HIV/AIDS. It is an avoidable collision of threats.
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