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Shabazz Novarra on Muck Rack

Shabazz Novarra

As seen in: The Journal of Biological Chemistry
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Articles

Crystal structure of the human 4-1BB/4-1BBL complex

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By Vaheh Oganesyan, Hamza Amdouni, Shabazz Novarra, Arnita Barnes
| The Journal of Biological Chemistry Verified
4-1BBL is a member of the tumor necrosis factor (TNF) superfamily and is the ligand for the TNFR superfamily receptor, 4-1BB. 4-1BB plays an immunomodulatory role in T cells and NK cells, and agonists of this receptor have garnered strong attention as potential immunotherapy agents. Broadly speaking, the structural features of TNF superfamily members, their receptors, and ligand-receptor complexes are similar.
Open in Who Shared Issue with article?

Crystal structure of the human 4-1BB/4-1BBL complex

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By Vaheh Oganesyan, Ryan N. Gilbreth, Hamza Amdouni, Shabazz Novarra
| The Journal of Biological Chemistry Verified
Author contributions: R.N.G. and M.B. conceptualization; R.N.G., V.Y.O., H.A., and S.N. formal analysis; R.N.G. and M.B. supervision; R.N.G., V.Y.O., H.A., S.N., L.G., and A.B. investigation; R.N.G., V.Y.O., S.N., L.G., A.B., and M.B. methodology; R.N.G., V.Y.O., S.N., and A.B. writing-original draft; R.N.G. and M.B. project administration; R.N.G., V.Y.O., S.N., A.B., and M.B. writing-review and editing.
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