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Shota Tanaka

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Japan
As seen in: Nature, Wiley Online Library, ScienceDirect, British Journal of Sports Medicine, Frontiers, MDPI, Taylor & Francis Online, Science Magazine, Royal Society of Chemistry, The Cureus Journal of Medical Science
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Articles

Longitudinal changes in DNA methylation in IDH-mutant glioma fuel disease progression through altered cell state differentiation

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By Masashi Nomura, Ramya Raviram, Joshua S. Schiffman, Lillian Bussema, John Lee, Yilin Fan, Florian Ruiz, Husain Danish, Ronan Chaligné, Jason T. Huse, W. K. Alfred Yung, Shota Tanaka, Nobuhito Saito, Sunit Das, Catherine Potenski, Dan A. Landau, Mario L. Suvà, Noelle Wheeler, Mian Hua Zheng, Sorcha Kellett, Labeeba Nusrat
| Nature Verified
Abstract The progression of isocitrate dehydrogenase-mutant glioma (IDH-G) from slow-growing tumor to fatal disease is associated with transcriptional and DNA methylation changes that remain poorly understood. Here, we profiled a longitudinal cohort of 36 IDH-G samples from 19 patients by joint-capture multi-omic single-nucleus DNA methylation, single-nucleus RNA sequencing and bulk exome sequencing.
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Comparing artificial intelligence and physician performance in predicting IDH mutation status in glioma

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By Satoshi Takahashi, Masamichi Takahashi, Manabu Kinoshita, Mototaka Miyake, Risa Kawaguchi, Akitake Mukasa, Kuniaki Saito, Motoo Nagane, Fumi Higuchi, Shota Tanaka, Nobuhiro Hata, Kaoru Tamura, Kensuke Tateishi, Ryo Nishikawa, Hideyuki Arita, Masahiro Nonaka, Takehiro Uda, Junya Fukai, Yoshiko Okita, Naohiro Tsuyuguchi, Yonehiro Kanemura, Fumiyasu Tsushima, Shingo Kakeda, Toshiaki Akashi, Toshiaki Taoka, Yoshiyuki Watanabe, Kei Yamada, Toshinori Hirai, Takashi Yoshiura, Jun Sese, Koichi Ichimura, Yoshitaka Narita, Ryuji Hamamoto, Naoki Shinojima, Ryohei Otani, Minako Azuma
| Nature Verified
Abstract Predicting isocitrate dehydrogenase (IDH) mutations in gliomas using magnetic resonance imaging (MRI) is clinically important for treatment planning. This study compared two artificial intelligence (AI) models, GliomaDepth-IDH (ResNet34-based) and GliomaVista-IDH (Vision Transformer-based), with 18 physicians (eight neuroradiologists, five neurosurgeons, and five neurosurgery residents) in predicting IDH mutation status.
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The Role of 18F-Fluorodeoxyglucose (18F-FDG) Positron Emission Tomography/Computed Tomography (PET/CT) Values in the Detection of Bladder Carcinoma

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By Shota Tanaka, Rika Yoshida, Takeshi Yoshizako
| The Cureus Journal of Medical Science
Specialty Please choose I'm not a medical professional. Allergy and Immunology Anatomy Anesthesiology Biostatistics Cardiac/Thoracic/Vascular Surgery Cardiology Critical Care Dentistry Dermatology Diabetes and Endocrinology Emergency Medicine Epidemiology and Public Health Family Medicine Forensic Medicine Gastroenterology General Practice Genetics Geriatrics Health Policy Hematology HIV/AIDS Hospital-based Medicine I'm not a medical professional.
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