Shu Ying Lu

Abstract Atherosclerosis (AS) remains a leading cause of cardiovascular morbidity worldwide. Strategies that promote autophagy and limit apoptosis hold therapeutic promise. Jingling Granules (JLG), a clinically used formulation, have shown vascular protective effects, but the underlying mechanisms are incompletely understood. Here, we investigated whether JLG attenuates atherosclerosis by modulating autophagy and apoptosis through mTOR signaling.

Correction to: Nature https://doi.org/10.1038/s41586-022-04673-6 Published online 27 April 2022 In the originally published version of this article, there was an inadvertent duplication of two panels/images in Extended Data Fig. 8, where the upper-left panel at 3 days was a duplicate of the upper-middle panel at 4 days in 8a, and the lower-left panel in 8b at 2 days was a duplicate of the lower-middle panel in 8a at 4 days.

Abstract Sepsis is a severe infectious disease with high mortality. However, the indicators used to evaluate its severity and prognosis are relatively complicated. The systemic inflammatory response index (SIRI), a new inflammatory indicator, has shown good predictive value in chronic infection, stroke, and cancer. The purpose of this study was to investigate the connection between sepsis and SIRI and evaluate its predictive usefulness.