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Changjun Yin

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Articles

Artery tertiary lymphoid organs encode a pathogenic high-affinity autoantibody−autoantigen pair in atherosclerosis

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By Chuankai Zhang, Xi Zhang, Yi Ran, Zhihua Wang, Liping Li, Shu Wang, Junjie Zheng, Yixin Zhang, Ting Sun, Yutao Li, Shu Ying Lu, Mingyang Hong, Zhe Ma, Sabine Steffens, Michael Hristov, Xavier Blanchet, Xinwen Dou, Xinyi Deng, Klaus Dornmair, Desheng Hu, Shibojyoti Lahiri, Axel Imhof, Nadja Sachs, Lars Maegdefessel, Jingyi Xiao, Jianning Zhang, Yan Wang, Hua Hong, Livia Habenicht, Xinyu Weng, Junbo Ge, Christian Weber, Donato Santovito, Rachael Bashford-Rogers, Sarajo Mohanta, Klaus Ley, Andreas Habenicht, Changjun Yin, Jingpu Zhu
| Nature Verified
Abstract Artery tertiary lymphoid organs (ATLOs) emerge in atherosclerosis, which is a chronic inflammatory artery disease with an autoimmune component. However, whether disease-relevant autoimmune B cells emerge in ATLOs remains unknown. In this study, we isolate germinal center (GC) B cells from ATLOs and lymph nodes from healthy and atherosclerosis-burdened mice, expression clone 60 autoantibodies and screen them for arterial wall reactivity.
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Dynamic network DEA efficiency of Chinese higher education institutions: insights from the teaching, research, and grant application subprocesses

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By Kok Fong See, Changjun Yin, Ming-Miin Yu
| Nature Verified
Abstract In the education community, there is widespread concern over the technical efficiency of higher education institutions (HEIs). To consider the internal structure of the efficiency measurement, network data envelopment analysis (NDEA) models have gradually been used in HEIs since 2010.
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PD-1 blockade unleashes local hepatitis B virus-related B cell response inhibiting hepatocellular carcinoma

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By Shuling Chen, Yuanqi Wang, Jingying Chen, Wenxuan Xie, Jianyu Chen, Guanrui Liao, Xiaoxue Ren, Kai Lei, Yuting Zhang, Shu Wang, Youmei Kang, QiaoYi Chen, Yixi Wen, Jiaming Lai, Pengyuan Yang, Shunli Shen, Shaoqiang Li, Johnson Lau, Changjun Yin, Ming Kuang
| Cell Press Verified
Keywords hepatocellular carcinoma tertiary lymphoid structures hepatitis B virus anti-PD-1 immune checkpoint blockade antibody affinity B-cell response Get full text access Log in, subscribe or purchase for full access. References 1. Vogel, A. ∙ Meyer, T. ∙ Sapisochin, G. ... Hepatocellular carcinoma Lancet. 2022; 400:1345-1362 2. McGlynn, K.A. ∙ Petrick, J.L. ∙ El-Serag, H.B. Epidemiology of hepatocellular carcinoma Hepatology. 2021; 73:4-13 3. Marron, T.U. ∙ Fiel, M.I. ∙ Hamon, P. ...
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