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As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Articles
An asymptomatic WASF1 truncation reveals pathogenic mechanism and therapeutic strategy for neurodevelopmental disorders
Abstract Introduction: Wiskott–Aldrich syndrome protein family member 1 (WASF1) truncating variants, such as c.1516C>T (p.Arg506Ter), are established causes of neurodevelopmental disorders (NDDs), but their underlying pathogenic mechanism remains debated. This study aimed to clarify the disease mechanism and identify potential therapeutic leads.
Model‐Informed Drug Development for Daprodustat Supports the Design of Individualized Dosing Regimens in Chronic Kidney Disease Patients With Anemia
GETTING THE DOSE RIGHT: A MODEL-INFORMED APPROACH TO INDIVIDUALIZED THERAPY Selecting the right dose is one of the most critical—and often most challenging—decisions in clinical drug development.
Origin of the metal in chondritic and achondritic lithologies of the Sierra Gorda 013 СBa‐like chondrite
Supporting Information Filename Description maps70005-sup-0001-TableS1.docxWord 2007 document , 42.7 KB Table S1. Measurements of the metal standards for the LA-ICP-MS analysis. References , and 1989. Abundances of the Elements: Meteoritic and Solar. Geochimica et Cosmochimica Acta 53: 197–214. , , and 2015. Pb-Pb Dating of Individual Chondrules from the CBa Chondrite Gujba: Assessment of the Impact Plume Formation Model. Meteoritics & Planetary Science 50: 1197–1216. , and 1999.
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