Silvia Naranjo

Abstract Limb function requires polarized anatomy across the dorsal-ventral (DV) axis, but it is unclear when the capacity for DV differentiation of paired appendages arose in evolution. Here we define ancestral DV patterning programs in the fins of fishes. We show that the orthologue of the limb dorsal determinant, Lmx1b, is required to establish dorsality in zebrafish pectoral fins and is regulated by a conserved LARM cis-regulatory hub.

Abstract Aging is one of the main challenges facing modern society. Understanding the cellular processes that occur in the later stages of life is essential to address age-related diseases. Although aging is a global process that affects the entire body, the brain is one of the most sensitive organs and is affected by numerous degenerative diseases. In this study, we investigate cell types and genes that are particularly sensitive to the aging process.

Cuando el trauma no se procesa adecuadamente, aparece el estrés postraumático: el cerebro sigue percibiéndolo como un peligro presente, lo que lleva a revivir la experiencia a través de recuerdos intrusivos, sensaciones angustiosas y una constante sensación de alerta. Existen tratamientos que pueden ayudar a paliar este trastorno. ¿QUIERES COLABORAR CON ETHIC?