Sindisiwe Dlamini on Muck Rack

Sindisiwe Dlamini

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As seen in: Nature

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Sindisiwe Dlamini’s Journalist Portfolio

Discovering different personalities through travel.

Discovering different personalities through travel.

By Sindisiwe Dlamini Growing up in Soweto, South Africa, life was vibrant and exciting. During my time in Joh…

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Trafalger High School disobeyed the authorities of apartheid

Trafalger High School disobeyed the authorities of apartheid

Picture by Google Trafalgar High school In 1912 after it was discovered...

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Statistics on the approaching national elections in 2024.

Statistics on the approaching national elections in 2024.

Picture by blindsa.org.za By Sindisiwe Dlamini A new National Assembly and each province's provincial legisla…

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Creepy but a Beautiful Roeland Street

Creepy but a Beautiful Roeland Street

By Sindisiwe Dlamini : Cape Town Roeland Fire Station Roeland Street has been a part of Cape Town's from the …

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Articles

Targeted next-generation sequencing implementation in Eswatini identifies rifampicin and bedaquiline resistance undetected by routine diagnostic testing

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By Debrah Vambe, Alexander Kay, Mangaliso Ziyane, Sein Sein Thi, Leonardo De Araujo, Viola Dreyer, Tanja Niemann Verified, Andrea Maurizio Cabibbe, Jennifer Furin, Lindokuhle Dlamini, Gugu Maphalala, Makhosazana Dlamini, Daniela Maria Cirillo, Anna M Mandalakas, Christoph Lange, Christian Utpatel, Sindisiwe Dlamini, Stefan Niemann Verified, Mdigo Thunzini, Busizwe Sibandze, Sijabu Masina, Tafadzwa Mazuruse, Thulani Jele, Bheki Mamba, Mbongeni Dube, Nomthandazo Lukhele, Sphiwe Ngwenya
| Nature Verified
Abstract In Eswatini, multidrug-resistant (MDR) Mycobacterium tuberculosis (Mtb) strains harbouring the rifampicin-resistance (RR) rpoB I491F mutation are missed by routine diagnostics, including GeneXpert MTB/RIF Ultra (Xpert Ultra), line probe assays (LPA), and mycobacterium growth indicator tube (MGIT) phenotypic drug susceptibility testing (pDST). To address this diagnostic gap, Eswatini introduced targeted next-generation sequencing (tNGS) in 2019.
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The future of diagnostics in Africa

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By Yenew Kebede, Nqobile Ndlovu, Susan Nabadda, Aytenew Ashenafi, Lara Vojnov, Rigveda Kadam, Ashley Kallarakal, Ilesh Jani, Angela Mushavi, Solange L. Baptiste, Gagandeep Kang, Kenneth Fleming, Kekeletso Kao, Jason Williams, Brian Kaiser, Renuka Gadde, William Rodriguez, William Rodríguez, Noah Fongwen, Anafi Mataka, Silver Mashate, Juliet E. Bryant, Pascale Ondoa, Neha Agarwal, Ravi Anupindi, Heidi Albert, Mikashmi Kohli, Nitika Pant Pai, Marguerite Massinga Loembé, Alaine Umubyeyi Nyaruhirira, Boghuma Kabisen Titanji, Nahid Bhadelia, Derrick E. Mimbe, Robia Islam, Fona Williams, Francine Ntoumi, Mohammed Lamorde, Adolfo Vubil, Arnab Pal, Sophie Magnet, Paolo Maggiore, Robert Luo, Sadia Shakoor, Grace Umutesi, Gonzalo J Domingo, Joseph E Bitilinyu-Bangoh, Collins Otieno, Gad Murenzi, Jane Carter, Francis Ocen, Lee F. Schroeder, Michael Wilson, Emily Gerth-Guyette, Tapiwanashe Kujinga, Fifa Rahman, Devan Dumas, Yashika Bansal, Zhi Zhen Qin, Lluís Donoso-Bach, Sindisiwe Dlamini, Celestina A. Obiekea, Konrad C. Bradley, Trevor Peter, Charles Sawadogo, Damian Fuller, Fatim Jallow, Sheick Oumar Coulibaly, Peter Ehrenkrantz, Chase Mertz, Smiljka De Lussigny, Anisa Ghadrshenas, Wayne Van Germet, Osborne Otieno, Obert Kachuwaire, Lucy Maryogo-Robinson, Sherrie Staley, Shiri Brodsky, Abha Patil, Miraf Mesfin, Sidharth Rupani, Mpaphi Mbulawa, Daniel Desalegn, Edwin Ochieng, Mary Mataranyika, Leon Biscornet, Namwaka Mulenga, Yucheng Tsai, Julie Ndasi, Thebora Sultane, Amadou Dieye, Ludovic Tamadea, Ana Capri, Davy Nsamba, Ignatius Awinibuno, Kingsley Odiabara, Zee Ndlovu, Ndeye Sambe, Rina Estelle
| Nature Verified
Abstract Persistent gaps in access to quality diagnostic tests undermine progress toward improved health outcomes and resilience to disease outbreaks in Africa. Furthermore, resources for strengthening laboratory systems have faced growing constraints owing to recent reductions in official direct financial assistance, highlighting an urgent need to identify investments that are high impact and minimally donor reliant.
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