Stefano Bartesaghi

Abstract Adaptation to the environment and extraction of energy are essential for survival. Some species have found niches and specialized in using a particular source of energy, whereas others—including humans and several other mammals—have developed a high degree of flexibility1. A lot is known about the general metabolic fates of different substrates but we still lack a detailed mechanistic understanding of how cells adapt in their use of basic nutrients2.

PML Loss Leads to Reduced Number of Stem Cells and Increased Number of Progenitors in the SVZ Loss of PML Leads to Reduction in Neuroblast Migration, Differentiation, and Olfactory Bulb Size PML Controls Cell Migration through Repression of the Axon Guidance Slit2 Gene An Association between PML, SLIT1, and Activation of the RAS Pathway in GBM In the adult mammalian brain, new neurons and glial cells continue to be generated in a germinal niche lining the lateral ventricles (subventricular...