Suheda Erener

Keywords intermittent fasting weight loss Langerhans’ islets β cells insulin glucose metabolism diabetes pancreas Research topic(s) CP: Metabolism Introduction Modern nutritional habits are characterized by an overconsumption of energy-dense and palatable foods, typically rich in lipids and carbohydrates.

Abstract Intermittent fasting (IF) is a nutritional lifestyle intervention with broad metabolic benefits, but whether the impact of IF depends on the individual's age is unclear. Here, we investigated the effects of IF on systemic metabolism and pancreatic islet function in old, middle-aged, and young mice. Short-term IF improved glucose homeostasis across all age groups, without altering islet function and morphology.

1Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada 2Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg, Germany 1Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada 1Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada 1Department of Cellular &...