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Articles

Targeting USP7 - a nano-therapeutic approach to restore and reactivate P53 for promoting apoptosis in glioma therapy

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By SUNNY KUMAR, Mrinal K. Ghosh
| Taylor & Francis Online
ABSTRACT Background Glioblastoma remains one of the most lethal brain malignancies due to its profound molecular heterogeneity, invasive biology, and poor drug penetration across the BBB. Clinically, USP7 is highly overexpressed and contributes to tumor aggressiveness in glioma. Methods Native USP7 inhibitors (P22077 and P5091) exhibit potent cytotoxicity but suffer from poor solubility, suboptimal pharmacokinetics, and limited BBB permeability, restricting their translational potential.
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Wilson Sonsini Advises Clair Health on $11.6 Million Seed Round

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By Seth Helfgott, SUNNY KUMAR, Michael Murrietta
| wsgr.com
Privacy Preference Center When you visit any website, it may store or retrieve information on your browser, mostly in the form of cookies. This information might be about you, your preferences or your device and is mostly used to make the site work as you expect it to. The information does not usually directly identify you, but it can give you a more personalized web experience. Because we respect your right to privacy, you can choose not to allow some types of cookies.
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Empirical Spatial Divergence and Heavy-Tail Error Analysis of FMCW Radar vs. LiDAR in Unstructured Traffic

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By Shubham Kumar, SUNNY KUMAR, Preetham Reddy Bannur
| preprints.org
You are already at the latest version This paper quantifies the spatial divergence between 128-channel Light Detection and Ranging (LiDAR) point clouds and Frequency Modulated Continuous Wave (FMCW) radar tracks in high-clutter urban environments using the TiAND dataset. Nearest-neighbor Euclidean distance between radar target centers and raw LiDAR geometry serves as the error metric, chosen because the dataset provides no semantic bounding-box annotations.
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