Sunwoo Oh

Correction to: Nature Structural & Molecular Biology https://doi.org/10.1038/s41594-024-01417-0, published online 3 January 2025. In the version of this article initially published, there was a typographical error in the Fig. 6c y-axis label, now reading “p65/GFP,” where “p65” originally read “p6.” The figure is now amended in the HTML and PDF versions of the article. About this article Bournique, E., Sanchez, A., Oh, S. et al.

Abstract Double-stranded RNAs (dsRNAs) produced during viral infections are recognized by the innate immune sensor protein kinase R (PKR), triggering a host translation shutoff that inhibits viral replication and propagation.

Abstract Antiviral DNA cytosine deaminases APOBEC3A and APOBEC3B are major sources of mutations in cancer by catalyzing cytosine-to-uracil deamination. APOBEC3A preferentially targets single-stranded DNAs, with a noted affinity for DNA regions that adopt stem-loop secondary structures.