Sydney Mason

Abstract Over the past two decades, photonic inverse design has emerged as a powerful approach to implement photonic devices with improved performance or to realize new functionalities. Whereas the efforts over the first decade focused on proof-of-concept devices designed and fabricated in university laboratories, the focus over the past 5–10 years has shifted towards implementation of scalable photonic systems.

Abstract Ageing is accompanied by declining memory function, with extremely heterogeneous manifestation in the human population1. Brain-extrinsic factors influencing cognitive decline, such as gastrointestinal signals, have emerged as attractive targets for peripheral interventions2,3,4,5,6, but the underlying mechanisms remain largely unclear.