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Taha Bartu Hayal

As seen in: The BMJ, Cell Reports
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Articles

Microglial clonal dynamics and the impact of clonal hematopoiesis in autologously transplanted rhesus macaques

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By Yifan Zhou, Diana Abraham, Taha Bartu Hayal, Ashley Gin, Xing Fan, Byung-Chul Lee, Taehoon Shin, Mario Roederer, George S. Vassiliou, Chuanfeng Wu, Cynthia E. Dunbar, Rohan V. Hosuru
| Cell Reports Verified
Keywords microglia rhesus macaques clonal hematopoiesis hematopoietic stem cell transplantation Research topic(s) CP: stem cell research CP: neuroscience Introduction Microglia are essential resident immune cells of the central nervous system (CNS).
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266 Efficient lentiviral transduction of genetically barcoded AntiCD20-CAR-IL15 cassette into peripheral blood-derived rhesus macaque NK cells using poloxamer 407 and CAR-NK in vitro and in vivo effects | Journal for ImmunoTherapy of Cancer

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By Chuanfeng Wu, David Allan, Taha Bartu Hayal, Aman A Mulla
| The BMJ Verified
Abstract Background Natural killer (NK) cells play a crucial role in immunosurveillance and antitumor immunity via detection and elimination of virally-infected or neoplastic cells.1 2 With a low risk of graft-versus-host disease following allogenic adoptive transfer and potent killing capabilities, NK cells have unique potentials for cell-based therapies as shown in recent proof-of-concept clinical trials, particularly via the introduction of targeted chimeric antigen receptors (CAR).3 4...
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