Taisho Yamada on Muck Rack

Taisho Yamada

As seen in: Nature, Cell Press
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Articles

A hierarchical Rorc(γt) cis -regulatory cascade orchestrates differentiation of RORγt⁺ innate immune cells

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By Takuma Fukui, Miyuki Watanabe, Reo Kobayashi, Taisho Yamada, Kenta Nakano, Kaori Tanaka, Akihito Harada, Tadashi Okamura, Koh-Hei Sonoda, Yasuyuki Ohkawa, Eriko Sumiya, Ruiqi Shao, Mikita Suyama, Ichiro Taniuchi, Satoshi Kojo, Shinichiro Sawa
| Cell Press Verified
Keywords RORγt ILC3 LTi cell RORγt+ APCs chromatin accessibility cis-regulatory elements pTreg priming Runx/CBFβ Introduction The nuclear hormone receptor RAR-related orphan receptor γt (RORγt), first identified in thymocytes,1 is a central regulator of type 3 immunity,2,3,4 orchestrating antimicrobial defense, tissue repair, and barrier homeostasis.
Open in Who Shared Issue with article?

RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells

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By Seiichi Sato, Yasuko Orba, Taisho Yamada, Yuki Sotoyama
| Nature Verified
Abstract Efficient immune responses against viral infection are determined by sufficient activation of nucleic acid sensor–mediated innate immunity1,2. Coronavirus disease 2019, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), remains an ongoing global pandemic. It is an urgent challenge to clarify the innate recognition mechanism to control this virus.
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