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Koh-Hei Sonoda on Muck Rack

Koh-Hei Sonoda

As seen in: Nature, PLOS ONE, Frontiers, Cell Press, Stem Cell Reports, The Journal of Biological Chemistry
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Articles

Two-year treatment outcomes in neovascular age-related macular degeneration with type 3 macular neovascularisation

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By Yosuke Fukuda, Satomi Shiose, Shoji Notomi, Yusuke Maehara, Kodai Yuge, Kenichiro Mori, Kohta Fujiwara, Kumiko Kano, Keijiro Ishikawa, Yusuke Murakami, Koh-Hei Sonoda, Kohei Kiyohara, Yuta Yasaka
| Nature Verified
Abstract Neovascular age-related macular degeneration (nAMD) with type 3 macular neovascularisation (MNV) carries a high risk of macular atrophy (MA) during anti-vascular endothelial growth factor (anti-VEGF) treatment. Previous studies have suggested that a greater injection burden is associated with a higher MA risk. We evaluated 2-year outcomes of patients with nAMD with type 3 MNV following the treat and extend (TAE) and pro re nata (PRN) regimens and identified the risk factors for MA.
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A hierarchical Rorc(γt) cis -regulatory cascade orchestrates differentiation of RORγt⁺ innate immune cells

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By Takuma Fukui, Miyuki Watanabe, Reo Kobayashi, Taisho Yamada, Kenta Nakano, Kaori Tanaka, Akihito Harada, Tadashi Okamura, Koh-Hei Sonoda, Yasuyuki Ohkawa, Eriko Sumiya, Ruiqi Shao, Mikita Suyama, Ichiro Taniuchi, Satoshi Kojo, Shinichiro Sawa
| Cell Press Verified
Keywords RORγt ILC3 LTi cell RORγt+ APCs chromatin accessibility cis-regulatory elements pTreg priming Runx/CBFβ Introduction The nuclear hormone receptor RAR-related orphan receptor γt (RORγt), first identified in thymocytes,1 is a central regulator of type 3 immunity,2,3,4 orchestrating antimicrobial defense, tissue repair, and barrier homeostasis.
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Histone methyltransferase Setd8 preserves chromatin accessibility to safeguard retinal progenitor cell identity during development

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By Sakurako Shimokawa, Hisanobu Oda, Yusuke Murakami, Koh-Hei Sonoda, Kinichi Nakashima, Taito Matsuda, Haruka Sekiryu, Kanae Matsuda-Ito
| Stem Cell Reports Verified
ArticleOnline now102789Open access 1Stem Cell Biology and Medicine, Department of Stem Cell Biology and Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan 2Division of Integrative Medical Oncology, Saiseikai Kumamoto Hospital, Kumamoto 861-4193, Japan 3Department of Ophthalmology, Graduate School of Medical Science, Kyushu University, Fukuoka 812-8582, Japan 4Laboratory of Neural Regeneration and Brain Repair, Division of Biological Science, Graduate...
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